ECEESPE2025 ePoster Presentations Metabolism, Nutrition and Obesity (164 abstracts)
Impact of B vitamin intake on weight loss outcomes in obese patients
Sana Khamassi 1 , Fatma Boukhayatia 1 , Haifa Abdesselem 1 , Emna Bornaz 1 , Nesrine Dhieb 2 , Kamilia Ounaissa 1 , Sana Hammami 3 , Houda Bouhajja 4 , Amel Gammoudi 2 , Awatef Kacem 2 , Emna Talbi 4 , Jamoussi Henda 2 & Chiraz Amrouche 1
1National Institute of Nutrition and Food Technology, Department of Nutritional Diseases D, Tunis, Tunisia; 2National Institute of Nutrition and Food Technology, Obesity Reserach Unit, Tunis, Tunisia; 3National Institute of Nutrition and Food Technology, Clinical Biology Laboratory, Tunis, Tunisia; 4National Institute of Nutrition and Food Technology, UR17SP01-Clinical Biology Laboratory, Tunis, Tunisia
JOINT3382
Background: Recent research has increasingly focused on the relationship between B vitamin intake and weight loss outcomes in obese individuals undergoing weight loss interventions. Numerous studies have examined how different B vitamins affect obesity-related factors, including body fat distribution and metabolic processes [1]. The aim of our study was to assess the impact of baseline B vitamin intake on weight loss outcomes in obese patients.
Methods: We conducted a longitudinal study involving 100 obese adult patients over 6 months. We analyzed body composition using SECA MBCA 515 bioimpedance at baseline and at follow-up. dietary survey data were collected at baseline using Nutrilog software. A balanced hypocaloric diet was prescribed and patients received regular follow-ups.
Results: The mean age was 44.42±13.25 years and the sex ratio (M/F) was 0.11. The mean fat mass (FM) and fat mass index (FMI) values were 52.50±12.39kg and 19.74±4.03kg/m2, respectively. The mean fat-free mass index (FFMI) was 20.34±2.53kg/m2 and 20% of the participants had a below-average FFMI at baseline. The deficiencies in vitamin B group intake observed at baseline were dominated by a deficiency in vitamin B9 (44%) and vitamin B2 (36%). At 6 month,22 patients were lost to follow-up and 78 patients completed the study with a mean body weight loss of 4.13 ± 6.90 %.The intake of vitamin B12 at baseline was positively correlated with the loss in BMI (P = 0.009), waist circumference (P = 0.009), and fat mass (P = 0.007), and inversely correlated with the loss in lean mass (P <0.001). In contrast, the intakes of vitamins B6 and B9 were inversely correlated with the loss of fat-free mass (P = 0.04 and 0.041, respectively), skeletal muscle mass (P = 0.038 and P = 0.011, respectively), and appendicular muscle mass (P = 0.021 and P = 0.024, respectively). However, the intake of vitamins B1, B2, B3, and B5 did not show any correlation with the different parameters of weight loss.
Conclusion: Our study underscores the importance of considering vitamin B intake, particularly B12, B6, and B9, when prescribing dietary interventions for weight loss in obese patients. Addressing potential deficiencies in these vitamins could enhance the effectiveness of weight loss strategies.
References: 1. Fu Y, Zhu Z, Huang Z, He R, Zhang Y, Li Y, et al. Association between Vitamin B and Obesity in Middle-Aged and Older Chinese Adults. Nutrients 2023;15:483.
Volume 110
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Endocrine Abstracts
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