ECEESPE2025 ePoster Presentations Pituitary, Neuroendocrinology and Puberty (220 abstracts)
Is partial empty sella or empty sella a risk factor for visual field defects?
Bernadetta Kałuża 1,2 , Mariusz Furmanek 3,4 , Paulina Siwik 5 , Nadia Bujnowska 5 , Jan Domański 1,2 , Aleksandra Żuk-Łapan 1,2 , Ewa Filipiak 5 , Jerzy Walecki 4,6 & Edward Franek 1,7
1Department of Internal Medicine, Endocrinology and Diabetology, National Medical Institute of the Ministry of the Interior and Administration. Students Scientific Group of the Medical University of Warsaw at the Department of Internal Medicine, Endocrinology and Diabetology, National Medical Institute of the Ministry of the Interior and Administration, Warsaw, Poland; 2Students Scientific Group of the Medical University of Warsaw at the Department of Internal Medicine, Endocrinology and Diabetology, National Medical Institute of the Ministry of the Interior and Administration, Warsaw, Poland; 3Medical University of Warsaw, Department of Pediatric Radiology, Warsaw, Poland; 4National Institute of Medicine of the Ministry of the Interior and Administration, Department of Radiology, Warsaw, Poland; 5National Institute of Medicine of the Ministry of the Interior and Administration, Department of Ophthalmology, Warsaw, Poland; 6Center of Postgraduate Medical Education, Department of Radiology, Warsaw, Poland; 7Mossakowski Medical Research Center, Polish Academy of Sciences, Department of Human Epigenetics, Warsaw, Poland.
JOINT2212
Background: Parasellar lesions may affect the optic chiasm leading to visual symptoms, such as a constricted visual field. However, partial empty sella and empty sella—despite involving subarachnoid space herniation into the sella turcica—may not produce vision abnormalities. The purpose of this study was to assess if empty sella and partial empty sella are risk factors for visual field defects.
Material and Methods: Out of 594 patients who had undergone pituitary magnetic resonance imaging (MRI), we selected 43 patients diagnosed with empty sella or partial empty sella syndrome, who subsequently underwent ophthalmological examination (86 eyes) with visual field assessment via full-field 120-point screening test, MRI of the pituitary and optic nerves, and hormone profile.
Results: The evaluated eyes were divided into two groups: Group 1: the eyes of patients with empty sella and the pituitary measuring < 3 mm craniocaudally (n = 46), Group 2: the eyes of patients with partial empty sella and the pituitary measuring ≥ 3 mm craniocaudally (n = 40). Patients from the study groups did not differ in terms of the extent of visual field defects (%) in the entire visual field (5.33±9.00 vs. 4.27±8.75, P = 0.455). Logistic regression analysis showed none of the following parameters: the pituitary craniocaudal diameter (OR 1.092; 95%CI [0.451–2.642], P = 0.846), pituitary volume (OR 0.995; 95%CI [0.987–1.003], P = 0.258), sellar volume (OR 1.00; 95%CI [0.999–1.001], P = 0.976), or MRI-measured optic nerve area (OR 1.002; 95%CI [0.996–1.008], P = 0.441) to be independent risk factors for defects in the entire visual field.
Conclusions: Neither the volume nor craniocaudal diameter of the pituitary is a risk factor for visual field defects.
Volume 110
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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