ECEESPE2025 ePoster Presentations Reproductive and Developmental Endocrinology (128 abstracts)
Time is testicular: early cryptorchidism care to avert tumors
Nada Ait Kassi 1 , Dounia Talbi 2 , Zineb Habbadi 1 , Fatima Toulali 1 , Ghizlane Sabbar 1 , Kaoutar Rifai 1 , Hinde Iraqi 1 & Mohamed El Hassan Gharbi 1
1Ibn Sina Hospital Mohamed V University, Endocrinology, Rabat, Morocco; 2Ibn Sina Hospital Mohamed V University, Endocrinology, Rabat, Morocco
JOINT7
Background: Cryptorchidism, or undescended testis, is a prevalent anomaly of the male genitourinary system and a well-established risk factor for testicular tumors. This case highlights the critical importance of early intervention in cryptorchidism to prevent malignancy.
Case Presentation: We report the case of a 54-year-old male with neglected bilateral cryptorchidism since childhood, presenting with abdominal pain and distension over the past three years. Imaging revealed intra-abdominal masses, leading to surgical resection, which confirmed bilateral testicular tumors. The patient underwent 25 sessions of chemotherapy with positive outcomes.
Investigations: Routine blood tests were normal. Imaging studies, including ultrasonography and contrast-enhanced CT, identified large homogeneous masses in the bilateral lumbar regions. The serum α fetoprotein (AFP) and β human chorionic gonadotropin (HCG) levels were normal, while lactate dehydrogenase (LDH) was elevated.
Outcome and Follow-up: The patient showed a favorable response to chemotherapy and remains under regular follow-up.
Discussion: Testicular tumors, predominantly germ cell tumors (GCTs), are the most common malignancies in men aged 20–40 years, with cryptorchidism increasing the risk by 4–6 times. Early orchidopexy significantly reduces malignancy risk by relocating the testis to the scrotum, thus promoting normal germ cell development. This case underscores the rarity of bilateral synchronous abdominal GCTs in cryptorchidism and highlights the necessity of early detection and intervention.
Conclusion: Prompt management of cryptorchidism is crucial in preventing malignant transformation and ensuring better patient outcomes.
Volume 110
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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