ECEESPE2025 ePoster Presentations Thyroid (198 abstracts)
Optimizing thyroid surgery: the critical role of intraoperative histological examination
Malika El Omri 1 , Nawress Thabet 1,2 , Habib Rouatbi 1 , Mouna Belakhdher 1 , Jihene Houas 1 , Monia Ghammam 1 , Abir Meherzi 1 , Hamza Elfekih 3 , Wassim Kermani 1 & Mohamed Abdelkafi 1
1Farhat Hached Hospital, Department of ENT and Head and Neck Surgery, Sousse, Tunisia; 2Farhat Hached University Hospital, ENT Department, Sousse, Tunisia; 3Farhat Hached Hospital, Department of Endocrinology, Sousse, Tunisia
JOINT3471
Background: In thyroid nodular pathology, intraoperative histological examination is a crucial diagnostic tool that helps guide surgical decision-making.
Objectives: To assess the accuracy and effectiveness of intraoperative histological examination in the management of thyroid nodules and to highlight its benefits and limitations as a real-time diagnostic tool during surgery.
Methods: This retrospective cross-sectional study analyzed 333 intraoperative histological examinations performed on thyroidectomy specimens at our ENT Department over a five-year period (January 2018 – December 2022).
Results: I this study the mean age of 47.45 years, with a strong female predominance (male-to-female ratio of 1:5.8). The most common reason for discovery was a palpable cervical mass (57.35%), while incidental detection via ultrasound accounted for 15.6%. Ultrasound findings revealed that multinodular goiters were more prevalent (61.6%) than solitary nodules (38.4%). Malignant tumors were diagnosed in 21.3% of cases, with the majority being papillary carcinoma (87.3%), followed by follicular carcinoma (9.8%), medullary carcinoma (1.4%), and anaplastic carcinoma (1.4%). Intraoperative examination identified 61 malignant cases, 259 benign cases, and 13 uncertain cases. When compared to the final histopathological examination across all histological types, intraoperative examination demonstrated a diagnostic accuracy of 93%, with a sensitivity of 85.9%, specificity of 100%, positive predictive value (PPV) of 100%, and negative predictive value (NPV) of 96%. The Youden index was 0.86. The sensitivity of intraoperative examination varied by histological type. It showed strong concordance with the final pathology report in 90.3% of papillary carcinomas and 100% of medullary and anaplastic carcinomas, but only 42.8% of follicular carcinoma cases. The rate of secondary surgical interventions following final histological examination was 3% (10 cases).
Conclusion: Intraoperative histological examination plays a pivotal role in the surgical management of thyroid nodules, offering rapid and precise diagnosis that optimizes surgical decision-making and minimizes the need for reoperations. Its high specificity and sensitivity enhance patient care by ensuring appropriate surgical intervention.
Volume 110
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2025 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more