Endocrine Abstracts

JOINT2903

Introduction: Thyroid surgery is usually performed when traditional drug therapy is ineffective, severe complications develop, or the risk of cancer is high. Recovery of body functions after surgery requires a certain period and specific treatments.

Aim: To study the recovery of thyroid function after total and subtotal thyroidectomy.

Materials and Methods: Between 2021 and 2023, 63 patients with thyrotoxicosis syndrome at RIIATEM were diagnosed with diffuse toxic goiter, nodular and multinodular toxic goiter, and underwent total and subtotal thyroidectomy. Of these patients, 11.1% were male, and 88.9% were female, with an average age of 43.48±2.92. A subtotal thyroidectomy was performed on 38.1% of the patients, and a total thyroidectomy on 61.9%.

Results: Pre-surgery TSH levels in the examined patients ranged from 18.7-22.6±1.0 mMe/ml; one month after surgery, these levels were 15.6±0.7 mMe/ml in patients with subtotal thyroidectomy and 26.87±1.08 mMe/ml in patients with total thyroidectomy, indicating clear signs of hypothyroidism. Three months post-surgery, the TSH levels were 10.4±0.7 mMe/ml after subtotal thyroidectomy and 12.37±0.78 mMe/ml after total thyroidectomy. Six months post-surgery, TSH levels decreased significantly to 6.3±0.5 mMe/ml in subtotal thyroidectomy patients and 7.9±0.86 mMe/ml in total thyroidectomy patients. One year post-surgery, the TSH levels were 1.9±0.2 mMe/ml after subtotal thyroidectomy and 1.75±0.17 mMe/ml after total thyroidectomy, nearing standard values. Conclusions Thus, the results after surgery indicate the effectiveness of the treatment, with a significant decrease in clinical manifestations of hypothyroidism in patients after thyroidectomy over the time. Immediate replacement therapy after total thyroidectomy thyroid function earlier reached normal ranges than in subtotal thyroidectomy.