Endocrine Abstracts

JOINT391

Introduction and Background: Papillary thyroid carcinoma (PTC), a form of well differentiated thyroid cancer, is a slow growing tumor and the commonest form of thyroid cancer in clinical practice, accounting for 80% of all thyroid cancers. Here we describe a case series of a one female sibling being diagnosed with Familial Papillary Thyroid Cancer after being symptomatic for a couple of months. After the surgery, other siblings did investigations and four others were diagnosed and treated for similar condition.

Case discussion: A 42 years old, married female was diagnosed as a case of FPTC. She is the oldest siblings to family of six siblings. The condition started with very delicate, pinpoint nodule in her neck that was associated with an irritating cough interfering with sleep and itching over the nodule. Later, as the mass was increasing in size, the patient started to complain of shortness of breath mainly at night the overall condition was associated with weight gain, heat intolerance, repeated miscarriage, generalized body swelling, palpitation, visual disturbance and double vision, and hair loss. Fine Needle Aspiration Cytology was not possible until 2 years has passed over symptoms. Later on, her siblings where diagnosed with FPTC following that by couple of years. The family has the history of Radiation exposure.