Endocrine Abstracts

JOINT3834

Introduction: Diabetic foot recurrence involves lesions reappearing after completely healing, leading to serious complications like amputations and decreased quality of life. This study identifies characteristics and predictive factors for recurrence.

Patients and Methods: This is an analytical retrospective cohort study conducted among patients hospitalized in our department for diabetic foot, including those who presented a recurrence from January 2018 to December 2024. Data were analyzed using IBM SPSS Statistics 27. 0. 1, with chi-square and Student’s t-tests used to identify significant associations with recurrence.

Results: Our study included 405 patients, 89 of whom had a recurrence (22%). The average age was 56. 7 years, with 78. 65% being over 50 years old. The male gender predominated with a sex ratio of 2. 8. 85. 6% of the patients had type 2 diabetes. The average duration of diabetes was 14. 35 years. The average Hba1c was 10. 24%. 79% of patients were on insulin. 21. 35% of cases had a history of amputation. Peripheral artery disease (PAD) was present in 46% of cases, diabetic retinopathy in 69. 6%, peripheral neuropathy in 55%, and autonomic neuropathy in 28%. The average duration of progression was 72 days. 51. 7% had a deformity. 40. 5% of the cases had bone involvement. Statistical analysis of our sample revealed several factors significantly associated with the recurrence of diabetic foot lesions: Age over 50 (P = 0. 03) has a notable impact on recurrence. Additionally, a longer duration of diabetes (P = 0. 019), insulin treatment (P = 0. 02), and glycemic imbalance (p < 0. 01) are key factors. Complications such as peripheral artery disease (PAD) (p < 0. 01), retinopathy (p < 0. 01), and peripheral neuropathy (p < 0. 01) play a crucial role. Bone involvement (P = 0. 03), a history of amputation and deformities (p < 0. 01) are also associated with recurrence.

Conclusion: Diabetic foot lesion recurrence is influenced by several factors, including age, duration of diabetes, treatment type, glycemic imbalance, presence of retinopathy, neuropathy, and peripheral artery disease (PAD), bone involvement, history of amputation, and foot deformity. Our study suggests that developing treatment strategies based on these factors could help prevent recurrences and improve patients’ quality of life.