Diagnostic and therapeutic specificity of thyroid nodules in children

Sabrine Farhani; Mehdi Ferjaoui; Oumaima Benkhalifa; Nawres Bouaziz; Rachida Bouatay; Amel Elkorbi; Naourez Kolsi; Harrathi Khaled; Jamel Koubaa

doi:10.1530/endoabs.110.P527

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Endocrine Abstracts (2025) 110 P527 | DOI: 10.1530/endoabs.110.P527

ECEESPE2025 Poster Presentations Endocrine Related Cancer (76 abstracts)

Diagnostic and therapeutic specificity of thyroid nodules in children

Sabrine Farhani ¹ , Mehdi Ferjaoui ¹ , Oumaima Benkhalifa ¹ , Nawres Bouaziz ¹ , Rachida Bouatay ¹ , Amel Elkorbi ¹ , Naourez Kolsi ¹ , Harrathi Khaled ¹ & Jamel Koubaa ¹

Author affiliations

¹ENT Department Fattouma Bourguiba Hospital Monastir Tunisia, ENT Department Fattouma Bourguiba Hospital Monastir Tunisia, Monastir, Tunisia

JOINT1787

Goals: To study the epidemiological, clinical, and therapeutic particularities of children operated on for thyroid nodules.

Patients and Methods: Retrospective study of 40 patients aged 18 or less who underwent surgery for thyroid nodules over a period of 15 and a half years [01/2010-06/2024].

Results: Forty children were operated on for thyroid nodules. The mean age was 15 years 8 months. The sex ratio (M/F) was 1/8. The mean duration of evolution was 4 months. The pathological history was noted to be Graves’ disease in 4 cases (10%), congenital hypothyroidism in 3 cases (7. 5%) and papillary thyroid carcinoma in the family in 1 case (2. 5%). The mode of discovery was a basicervical swelling in the majority of cases. Cervical ultrasound was systematically requested in all our patients with a chest CT scan in 2 cases and a thyroid scintigraphy in 4 cases. Fine needle aspiration cytology was performed in 3 cases (7. 5%). Surgery consisted of total thyroidectomy in 23 cases (57. 5%), loboishmectomy in 17 patients (42. 5%), accompanied by mediastinal-recurrent lymph node dissection in 12 cases (30%) and functional in 2 cases (5%). Definitive histology concluded with papillary carcinoma in 11 cases (27. 5%), encapsulated vesicular with limited angioinvasion in 1 case (2. 5%). The evolution was favorable in all patients with a mean follow-up of 6 months.

Conclusion: Thyroid nodules are rare in children. They are more aggressive than in adults. A malignant lesion must be suspected in time and treated promptly.