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Endocrine Abstracts (2026) 117 P246 | DOI: 10.1530/endoabs.117.P246

1Oxford Centre for Diabetes, Endocrinology and Metabolism, Oxford, United Kingdom; 2Cardiff University School of Medicine, Cardiff, United Kingdom; 3Great Western Hospital, Swindon, United Kingdom; 4Kings College Hospital, NHSFT, London, United Kingdom; 5University College London Hospital, London, United Kingdom; 6Frimley Health NHSFT, Slough, United Kingdom; 7Royal Surrey County Hospital, Guildford, United Kingdom; 8Royal Berkshire Hospital, Reading, United Kingdom; 9Royal Infirmary of Edinburgh, Edinburgh, United Kingdom; 10Royal Bournemouth Hospital, Bournemouth, United Kingdom; 11Ninewells Hospital, Dundee, United Kingdom


Thyroid eye disease (TED), is a frequent extrathyroidal manifestation of Graves’ disease, affecting 25-50% of patients, impacting vision and quality of life with delayed recognition resulting in poor clinical outcome. The Thyroid Eye Disease Amsterdam Declaration Implementation Group (Teamed) principles were initiated in 2009 [2] to improve management of patients with TED. The Team ED 5 objectives aimed to promote better care for patients with, or at risk of TED with 5 key recommendations; accurate diagnosis of Graves’ disease, screen all patients for TED, alert patients to risk, prevent deterioration and early referral to eye specialist clinic. The aim of national multi-centre retrospective audit was to assess the effectiveness of this approach, with a standardised audit tool developed and applied across 9 centres*. It included patients with new or relapsed GD diagnosis seen in endocrinology clinics for 6 months (July - Dec 2024). There was a cohort of 566 patients with an average age of 46.3 years and female preponderance (80%). It was encouraging to see 93% of patients were accurately diagnosed on basis of TRAB testing. Clinicians recognized TED in 2/3rd of cases though standardized CAS scoring was only done in 13.6 % of patients and the early warning card was offered only in 6.8% of cases. Smoking status was documented in 48.8% of cases, 9.7% of which were active smokers. Smoking cessation advice was documented as given to only 10% of patients. The results suggest that although accurate diagnosis of GD and screening for TED is prevalent in clinics, further work is needed in optimizing care. Endocrinologists can play a key role by increasing patient awareness via TED early warning card, addressing smoking as an important modifiable risk factor, maintaining euthyroid profile and liaison with ophthalmologist in multi-disciplinary clinic for moderate -severe TED.

Volume 117

Society for Endocrinology BES 2026

Harrogate, United Kingdom
02 Mar 2026 - 04 Mar 2026

Society for Endocrinology 

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