Searchable abstracts of presentations at key conferences in endocrinology

ea0011p723 | Reproduction | ECE2006

Isolated progesterone secretion by an ovarian Leydig cell tumour: I, hormonal and immunohistochemical characterization II, effects on the gonadotrope axis

Bry H , Meduri G , Abirached F , Constancis E , Brailly S , Chanson P , Young J

A 20 yr old woman was referred for primary amenorrhea. At examination BMI was 19 and displayed a pubertal development at S4P4. Hormonal evaluation showed normal prolactin, low estradiol (18 pg/ml) and gonadotropins (LH=1.5IU; FSH=1.9 IU/L). Testosterone was normal (0.25 ng/ml) but curiously plasma progesterone (P) was increased (from 3.9 to 5 ng/ml). Initial ovarian sonography and adrenal CT scan didn’t show any abnormal mass. ACTH stimulation tests showed normal response...