Endocrine Abstracts

Cardiac arrhythmias in thyrotoxicosis are usually seen as sinus tachycardia and atrial fibrillation but conduction abnormalities in the form of heart blocks do occur in rare instances. We present here four hyperthyroid patients with complete heart blocks. Cases 1 and 2 are young women diagnosed with Graves’ disease who both experienced syncope and were seen to have 3rd degree atrio-ventricular block. Case 3 is a young woman who presented with palpitations, fever and short...

Objective: Evaluate the markers of oxidative stress and antioxidants status in patients with gestational diabetes (GD).Material and methods: We performed a nested case-control study within a sample of a total of 126 pregnant women between the 24 and 29 weeks. Of the 126 women studied we compared 63 with GD and 63 control pregnant women. Both groups were analyzed for demographic data, perinatal and obstetrics results and the levels of the markers oxidativ...

Objective: Evaluate the proinflammatory and anti-antinflamatory adipokines in patients with gestational diabetes (GD).Material and methods: We performed a nested case-control study within a sample of a total of 126 pregnant women between the 24 and 29 weeks. Of the 126 women studied we compared 63 with GD and 63 control pregnant women. Both groups were analyzed for demographic data, perinatal and obstetrics results and the plasma levels of the tumor necr...

Objectives: To evaluate the prevalence of subclinical hypertension detected by ambulatory blood pressure monitoring (ABPM) and its relationship with some clinical and epidemiological factors in normotensive and normoalbuminuric patients with type 1 diabetes.Patients and methods: Transversal study that included patients with type 1 diabetes, older than 18 years, with clinic blood pressure lower than 130/80 mmHg and absence of microalbuminuria. Twenty-four...

Objectives: To determine the lifestyle in patients with morbid obesity in a previous group and in a group after performing bariatric surgery.Material and methods: Cross-sectional study in two groups of patients with morbid obesity one before and one after bariatric surgery attended in the Clinical Management Unit of Endocrinology and Nutrition of the Puerta del Mar Hospital in Cádiz. The clinical and analytical data of the patients, the sociodemogra...

Objectives: To evaluate the psychosocial aspects in a group of patients in follow-up in specific consultation of bariatric surgery prior to the intervention and in a group of patients intervened.Methods: Cross-sectional study of patients in follow-up in the specific morbid obesity consultation of the University Hospital Puerta del Mar (Cádiz) not intervened and a group intervened and in a group intervened, at 6–12 months of follow-up.<p cla...

Background: Patients with type 2 diabetes face daily challenges in making dietary choices that are influenced by eating behaviors. Recognition of eating behaviors and associated demographic profiles could aid in individualizing dietary plans and direct nutrition programs in forming cost-effective measures.Objective: The goal of this study is to identify differences in eating behaviors across demographic profiles of Filipinos with type 2 diabetes.<p c...

The relationship between gestational diabetes mellitus (GDM) and oxidative stress is not well known and the effect of oxidative stress in GDM placenta and the impact that could have on perinatal morbidity and risk of future complications is also yet to be elucidated. The aim of the study was to evaluate the relationships between maternal and placental tissue levels of markers of oxidative stress and antioxidants in women with GDM, which potentially may have considerable clinic...

Pituitary carcinomas are rare but represent a particular challenge to clinical practice. We report a case of pituitary carcinoma with metastatic disease in a separate non-contiguous foci within the central nervous system. A 64 year old man presented with a large non-functioning pituitary adenoma manifesting as headache, third pair of cranial nerves paralysis, panhypopituitarism and impaired visual acuity in 1996.The tumour was grossly removed through a right pterional cranioto...

Cannabinoids and ghrelin exert hypothalamic orexigenic effects and independent peripheral effects have also been reported. We have recently reported that ghrelin and cannabinoids can stimulate hypothalamic and heart AMPK activity, and can inhibit liver and adipose tissue AMPK activity, in rats (Kola et al., JBC, 2005). These data are concordant with the known orexigenic, adipogenic and diabetogenic effects of these compounds as well as with their beneficial effects on t...