Searchable abstracts of presentations at key conferences in endocrinology

ea0020p244 | Bone/Calcium | ECE2009

Effect of one year treatment with strontium ranelate on bone mineral density in women with established osteoporosis previously treated with teriparatide

Anastasilakis Athanasios , Polyzos Stergios , Avramidis Avraam , Papatheodorou Athanasios , Terpos Evagellos

Teriparatide (TPTD – recombinant human parathyroid hormone 1–34) markedly increases bone mineral density (BMD) and reduces fracture risk. Sequential treatment with an antiresorptive agent is believed to preserve or further increase BMD. Strontium ranelate (SR) is thought to uncouple bone remodeling resulting in increased BMD and reduced fracture risk. In this prospective study, we aimed to evaluate the effect of SR on BMD in women with established osteoporosis previo...

ea0011p344 | Diabetes, metabolism and cardiovascular | ECE2006

Acute and chronic effect of teriparatide on glucose metabolism in women with established osteoporosis

Anastasilakis A , Goulis DG , Koukoulis G , Slavakis A , Kita M , Avramidis A

Introduction: There is indirect evidence of unfavorable effects of parathyroid hormone (PTH) on glucose metabolism. Teriparatide (recombinant human PTH 1-34 - TPTD) has been recently available for the treatment of osteoporosis.Aim: To evaluate the acute and chronic effect of TPTD on blood glucose and insulin levels in women with established osteoporosis.Patients and methods: Twenty-three postmenopausal women with established osteop...

ea0063gp204 | Diabetes: Pharmacotherapy | ECE2019

Fasting insulin levels correlate with the incidence of hypoglycemic events in patients with Type 2 Diabetes treated with sulfonylureas: a retrospective cross-sectional study

Kolokas Konstantinos , Koufakis Theocharis , Avramidis Iakovos , Gerou Spyridon , Chatzidimitriou Maria , Kazakos Kyriakos , Karras Spyridon , Kotsa Kalliopi

Background: Sulfonylureas (SUs) are known to increase fasting insulin levels in patients with Type 2 Diabetes (T2D) treated with these agents. Whether this increase is related to a greater risk of hypoglycemia has not yet been sufficiently elucidated.Methods: The study included 58 patients with T2D who had been on treatment with SUs, but not insulin, for more than 2 years. Confirmed hypoglycemic episodes during the past year were self-reported by the pat...

ea0016p94 | Bone and calcium | ECE2008

Scintigraphic, biochemical and clinical response to zoledronic acid treatment in patients with Paget's disease of bone

Avramidis Avraam , Polyzos Stergios , Moralidis Efstratios , Arsos Georgios , Efstathiadou Zoe , Karakatsanis Konstantinos , Grollios Georgios , Kita Marina

Introduction: Bisphosponates have long been used with success in the treatment of Paget’s disease of bone (PDB). The aim of this study was to evaluate the early (up to three months) and late (at twelve months) scintigraphic, biochemical and clinical response to a single intravenous infusion of zoledronic acid (ZOL) in patients with PDB serially assessed for one year.Materials and methods: Nine patients with 30 bone lesions due to PDB were prospectiv...

ea0014p265 | (1) | ECE2007

Influence of orlistat on adiponectin levels in obese women

Tzoitou Marianthi , Papadopoulou Evridiki , Papageorgiou Athanasios , Galactidou A , Kita Marina , Kourtis Anargyros , Poulakos Pavlos , Avramidis Avraam

Introduction: Adiponectin is secreted by adipocytes and has been linked to glucose and lipid regulation. Obesity, diabetes and atherosclerosis have been associated with reduced adiponectin levels. Orlistat lowers lipids and improves insulin sensitivity but its effect on other metabolic parameters is not known.The purpose of this study is to evaluate the influence of orlistat on metabolic and hormonal parameters of the adipose tissue.<p class="abstext...

ea0014p381 | (1) | ECE2007

Resistin levels in hypothyroid patients before and after treatment &br;with thyroxin

Tzoitou Marianthi , Papadopoulou Evridiki , Galactidou A , Papageorgiou Athanasios , Kourtis Anargyros , Kita Marina , ventzi louiza , Avramidis Avraam

Introduction: Resistin is a peptide hormone that is secreted from fat cells and its secretion is regulated from hormonal and dietary factors. In hypothyroid patients its levels are decreased.The purpose of this study is to evaluate the levels of circulating resistin in hypothyroid patients before and after thyroid function is normalized with thyroxin therapy.Materials and methods: Twenty (20) hypothyroid patients (2M, 18F) mean age...

ea0011p658 | Reproduction | ECE2006

Endothelin-1 levels in men of reproductive age with idiopathic hypogonadism after treatment with tamoxifen or raloxifene

Tzoitou M , Papadopoulou E , Papageorgiou A , Kita M , Zournatzi V , Kourtis A , Avramidis A , Panidis D

An association between testicular function and vasoconstrictive peptide endothelin-1 levels, which is produced by Leydig and Sertoli cells, is observed. Endothelin –1 regulates blood flow in the testis and stimulates testosterone secretion.The purpose of this study is (1) to estimate the influence of tamoxifene and raloxifene therapy on enthothelin-1 levels in men of reproductive age with idiopathic hypogonadism. (2) To find an association between i...

ea0016p802 | Thyroid | ECE2008

Serum thyrotropin concentration as a biochemical predictor of thyroid malignancy in patients presenting with thyroid nodules

Polyzos Stergios , Kita Marina , Efstathiadou Zoe , Poulakos Pavlos , Slavakis Aristidis , Sofianou Danae , Flaris Nikolaos , Leontsini Maria , Kourtis Anargyros , Avramidis Avraam

Background: Fine-needle aspiration biopsy is the ‘gold standard’ in the preoperative management of thyroid nodules.Aim: The aim of this study was to investigate whether serum TSH is a predictor of thyroid malignancy in patients presenting with thyroid nodules.Subjects and methods: About 565 patients without overt thyroid dysfunction, who presented with palpable thyroid nodule(s) between 1988 and 2004 and underwent at leas...