Endocrine Abstracts

Introduction: We aimed to evaluate the relationship between platelet count and metabolic risk factors in over weight and obese women in Turkish women.Methods: Over weight (BMI>25 kg/m2) 665 and obese (BMI>30 kg/m2) 4609 women were enrolled into the study. The patients were divided into three group according to the platelet count (PLT), Group I (n=1724) consist of serum PLT≤245×103, group II (n...

Introduction: Hypertension is a major risk factor for several cardiovascular diseases including coronary heart disease. Prehypertension is defined systolic blood pressure (SBP) between 120–139 mmHg and diastolic blood pressure (DBP) 80–89 mmHg. Recent studies have documented an increased risk of cardiovascular disease in persons with prehypertension. In this study, we evaluated association between prehypertension and the metabolic risk markers in over weight and obes...

Introduction: Elevated levels of the inflammatory markers are associated with increased risk for CVD and diabetes mellitus. There is accumulating evidence indicating that inflammatory markers as C-reactive protein (CRP) is associated with insulin resistance. The aim of the study is to evaluate the correlations between serum inflammatory markers and plasma fasting glucose (PFG) in overweight and obese women.Methods: Overweight (25<BMI<30 kg/m...

Introduction: This study carried out relationship between glomerulary filtration rates (GFR) and various metabolic parameters in obese women.Materials and methods: Selected subjects recruited retrospectively from outpatient clinic for this study were 5115 overweight or obese women with mean GFR which was 93 ml/dk/1.73 m2 calculated by MDRD (modification of diet in renal disease). According to mean GFR, they divided group I (low GFR) having &#8...

Introduction: Elevated high-sensitive c-reactive protein (hs-CRP) in association with hyperinsulinemia, obesity, insulin resistance and high blood pressure are significant risk factors for cardiovascular diseases. The aim of this study is to evaluated the correlations between serum hs-CRP concentration and metabolic risk factors in overweight and obese women.Methods: Overweight (BMI>25 kg/m2) and obese (BMI>30 kg/m2) 755 wom...

Introduction: It was shown that a relationship between uric acid and cardiovascular diseases, and hyperuricemia is associated with systemic inflammation. But, determination of uric acid is widely available and inexpensive, it has been overlooked as a marker of systemic inflammation and metabolic disturbances. In this study, we aimed to evaluate uric acid value and its association with inflammation and metabolic disturbances in overweight and obese Turkish women.<p class="a...

Aim: Increased levels of fasting parathyroid hormone(PTH) have been hypothesized to influence increased levels of body fat mass. Preliminary studies show that serum PTH levels are higher in obese than in non-obese young adults and decline with weight loss. In the present study, it was aimed to evaluate relationship between antropometric and metabolic risk parameters and PTH levels in Turkish women.Materials and methods: Analyses were performed on 710 Tur...

Aim: Serum calcium levels have a relation glucose homeostasis and weight management, and controversies in findings. This study carried out relationship between serum calcium levels and various metabolic parameters in obese Turkish Women.Materials and methods: Subjects for this study were 3544 overweight or obese Turkish women with mean level of serum calcium 9.4 md/dl. According to mean calcium level, they divided group I having >9.4 mg/dl and group ...

Introduction: Age at menarche reflects various health aspects including the timing of sexual maturation, growth and nutritional status, and enviromental conditions. This study carried out assesment obesity risk and the relationship between obesity, metabolic parameters and age at menarche in a series of Turkish women.Materials and methods: In a survey of obesity outpatient clinic, 4212 women who have mean age 38.5±12.1 years and ages at menarche bet...

Homozygous familial hypercholesterolemia (HoFH) represents a potentially fatal condition that is caused by low density lipoprotein (LDL) cholesterol receptor deficiency. Statins alone are not effective in HoFH. In recent years, semiselective or selective LDL cholesterol apheresis systems have been shown to prolong life. However, applying LDLC apheresis therapy, recent evidence also suggests that more intense LDL cholesterol reduction is associated with more clinical benefit. E...