Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep843 | Reproductive and Developmental Endocrinology | ECE2020

Hyperandrogenism in a postmenopausal woman secondary to an androgen secreting steroid cell tumor of the ovary

Bastos Filipa , Franco Sara , Ferreira Ana , Manita Isabel , Portugal Jorge

Introduction: Androgen secreting neoplasms of the ovary are rare and usually show autonomous secretion. Steroid cell tumors of the ovary represent less than 0.1% of all ovarian tumors and are a subgroup of sex cord-stromal tumors. In most cases, patients present with androgenic clinical features.Case report: A 58-year-old woman complained of rapid onset of androgenic alopecia, excessive hirsutism and clitoromegaly. Endocrine assessment showed high levels...

ea0016p214 | Diabetes and cardiovascular diseases | ECE2008

Kidney transplantation and diabetes mellitus: continuous monitoring of glucose

Baptista Carla , Bastos Margarida , Guimaraes Joana , Leitao Patricia , Melo Miguel , Santos Jacinta , Barros Luisa , Bastos Carlos , Alves Rui , Carrilho Francisco , Mota Alfredo , Carvalheiro Manuela

Introduction: The benefits of intensive management of type 1 and type 2 diabetes have been well established in several studies, as DCCT and UKPDS, and include reduced of long term complications. Current guidelines target of A1c<7% is also to achieve in diabetic patient with kidney transplant. Methods to improve patient’s ability to achieve this goal are being explored. Continuous monitoring of glucose in interstitial fluid allows the identification of glycemic excursi...

ea0055wa13 | Workshop A: Disorders of the hypothalamus and pituitary (I) | SFEEU2018

Cushing’s disease relapse associated with central diabetes insipidus

Ferreira Ana , Silva Tiago , Bastos Filipa , Manita Isabel , Cordeiro Maria Carlos , Portugal Jorge

Introduction: Central diabetes insipidus (DI) is a frequent complication of transfenoidal surgery for Cushing’s disease (CD). It can be transient or, more infrequently, permanent. The most common mechanism results from surgical neurohypophyseal damage rather than local mass effect from the pituitary adenoma.Case report: A 40 years old woman was referred to our Endocrinology outpatient clinic at the beginning of 2015 for new onset hypertension, signi...

ea0081ep171 | Calcium and Bone | ECE2022

A sporadic case of pseudohypoparathyroidism type Ib and fahr’s syndrome

Araujo Catia , Ferreira Mafalda Martins , Araujo Barbara Filipa , Lavrador Mariana , Baptista Carla , Bastos Margarida , Paiva Isabel

Introduction: Pseudohypoparathyroidism is a heterogeneous disease characterized by hypocalcemia, hyperphosphatemia and parathyroid hormone resistance. The distinct pseudohypoparathyroidism types are distinguished by physical features, the coexistence of other hormone resistances and genetic defects. Pseudohypoparathyroidism type Ib is more often associated with sporadic cases, unlike others types.Clinical Case: Male, born in France, diagnosed with pseudo...

ea0063p1076 | Pituitary and Neuroendocrinology 3 | ECE2019

Prolactinoma – is there a relationship between T2W signal intensity in MRI and response to treatment with dopamine agonists?

Ferreira Ana , Oliveira Guilherme , Bastos Filipa , Carlos Cordeiro Maria , Duarte Julia , Portugal Jorge

Introduction: Prolactinomas are mostly benign tumours usually managed with pharmacological treatment. Some, however, seem to be resistant to dopamine agonists (DA) for unclear reasons. The relationship between T2W signal intensity (T2WSI) and response to treatment with somatostatin analogs is well described in acromegaly patients. Some evidence suggests that prolactinoma’s T2W hypointensity might be related to higher baseline prolactin levels and more resistance to DA.</p...

ea0063p1081 | Pituitary and Neuroendocrinology 3 | ECE2019

ACTH-positive diffuse idiopathic neuroendocrine cell hyperplasia (DIPNECH)

Ferreira Ana , Bastos Filipa , Pedro Paula , Lopes Miguel , Carlos Cordeiro Maria , Portugal Jorge

Introduction: DIPNECH is a preinvasive condition in which there is an idiopathic generalised proliferation of pulmonary neuroendocrine cells that can form tumourlets. There are very few cases described of ACTH secretion by these cells causing Cushing’s syndrome, some of them cyclic.Case report: A 41 year-old woman was sent to our Endocrinology outpatient clinic for menstrual disturbance, acne and excessive sweating. She had a recent diagnosis of DIP...

ea0041ep985 | Thyroid (non-cancer) | ECE2016

Clinical, imaging and cytological differences between palpable and non-palpable thyroid nodules

Silva Joao , Paiva Sandra , Ribeiro Cristina , Melo Miguel , Gomes Leonor , Bastos Margarida , Carrilho Francisco

Introduction: The prevalence of palpable nodules varies between 3–7% and nodules diagnosed by ultrasonography between 20–76%. According to the American Thyroid Association’s guidelines it isn’t recommended to perform routine thyroid ultrasound for thyroid nodules diagnosis, unless they are palpable or there are any risk factors.Objective: Evaluation of sonographic and cytological differences between palpable and non-palpable thyroid n...

ea0040p15 | (1) | ESEBEC2016

Post-pancreatectomy persistent adult nesidioblastosis: follow-up of 24 years

Almeida Raquel , Santos Ana Paula , Gomes Jose Teixeira , Lima Bastos , Bacelar Conceicao

Introduction: Adult nesidioblastosis is a rare entity that has motivated the publication of several case reports, but long-term outcomes are rarely described. Distal or sub-total pancreatectomy is indicated in cases of severe symptoms or lack of response to medical treatment. We report the case of a patient with persistent nesidioblastosis after pancreatectomy keeping under medical treatment for 24 years.Clinical case: Woman currently with 81-years old, ...

ea0029p128 | Adrenal medulla | ICEECE2012

Pheochromocytoma in neurofibromatosis type 1

Moreno C. , Bastos M. , Ruas L. , Vieira A. , Alves M. , Gouveia S. , Saraiva J. , Carvalheiro M.

IntroductionNeurofibromatosis type 1 (NF-1) is a relatively frequent syndrome, with an estimated incidence of 1/3000 per year. Patients with NF-1 are at an approximately fourfold higher risk of developing tumors than the general population, most frequently gastrointestinal stromal tumors, central nervous system tumors and endocrine tumors. Pheochromocytoma may occur in about 1% of these patients.Case report: We report a 56-year-old...

ea0029p402 | Clinical case reports - Thyroid/Others | ICEECE2012

Pendred’s syndrome: genetics and phenotypic variability

Alves M. , Bastos M. , Vieira A. , Gouveia S. , Saraiva J. , Moreno C. , Carvalheiro M.

Background: Pendred syndrome (PS) is an autosomal recessive disorder characterized by defective organification of iodine, goiter and deafness. It is caused by mutations in pendrin gene (SLC26A4), a transporter of chloride/iodide that mediates the efflux of iodine from thyroid follicular cells to the follicular lumen.Clinical case: Case-index: MJFS, female, refered to consultation at 35 years for enlarged neck. Personal history: congenital deafness, thyro...