Searchable abstracts of presentations at key conferences in endocrinology

ea0022p111 | Bone/Calcium | ECE2010

Osteoporosis and osteopenia in patients after the organ transplantation

Brunova Jana

Background: Survival of patients after the transplantation (Tx) of solid organs is improving. Osteoporosis and bone fractures belong to their long-term complications. The contributing factors are disturbances of bone metabolism in pre-transplant period and immunosuppressive therapy including corticosteroids after the transplantation.Patients and methods: We investigated the prevalence of osteoporosis and osteopenia in 248 diabetic patients after the Tx o...

ea0070aep183 | Bone and Calcium | ECE2020

The bone density and trabecular bone score in patients after solid organ transplantation

Brunova Jana , Kratochvilova Simona

Introduction: Organ transplant recipients are at increased fracture risk compared to general population. Bone mineral density (BMD), predictive of fracture in general population, does not reflect impaired bone quality frequently present in patients with advanced organ failure. Trabecular bone score (TBS) provides surrogate measures of bone microarchitecture and therefore helps to identify persons at risk for fracture among transplant recipients.Methods: ...

ea0026p6 | Adrenal cortex | ECE2011

CT imaging in patients with adrenal incidentaloma

Brunova J , Bruna J

Adrenal masses which are found unexpectedly with US or CT examination of abdomen are called adrenal incidentalomas. The aim of study was to evaluate the contribution of imaging characteristics of incidentally discovered adrenal mass to the differential diagnosis.We have studied 60 patients with adrenal mass (21 M, 39 F, age 34–85 years) who had CT scan of abdomen for various diagnoses but they were not suspected to have adrenal pathology. The right ...

ea0011p559 | Growth and development | ECE2006

Morphological changes of pituitary region in primary GH deficiency

Bruna J , Brunova J

Purpose of study: The study was focused on MRI of morphological changes of pituitary gland, pituitary fossa and surrounding structures in patients with primary growth failure. We evaluated MRI, clinical status and hormonal changes in 18 patients with primary growth failure referred to University Hospital.Methods and patients: We examined 18 patients (10 male, 8 female), average age 18.3 (2–34) years. All patients had a severe growth hormone deficien...

ea0041gp35 | Bone & Calcium Homeostasis | ECE2016

Retrospective analysis of bone metabolism in patients waiting for simultaneous pancreas kidney transplantation

Kratochvilova Simona , Zahradnicka Martina , Brunova Jana

Objective: Osteoporosis is a typical long-term complication after solid organ transplantation. Patients after simultaneous pancreas kidney transplantation (SPK) are at a very high risk due to preceding renal osteopathy and diabetic status. To determine the best preventive strategy we analysed the bone metabolism at the point of the pretransplant examination.Design and methods: In years 2011–2014 the number of 112 patients with type 1 diabetes (69 me...

ea0041ep122 | Bone & Osteoporosis | ECE2016

Osteoporosis therapy with denosumab in patients after solid organ transplantation

Brunova Jana , Kratochvilova Simona , Bruna Josef

Introduction: The transplantation- associated osteoporosis became an increasingly important problem with the better survival of patients after the solid organ transplantation (Tx). Adequate vitamin D intake, calcium supplementation and bisphosphonates therapy are currently recommended for osteoporosis treatment. However bisphosphonates may be limited with patients’ impaired renal function. Denosumab use is the possible option but till now only a little data exist in solid...

ea0037gp.10.04 | Calcium, Vitamin D and Bone | ECE2015

Osteoporosis and osteopenia in patients after kidney and pancreas transplantation

Brunova Jana , Kratochvilova Simona , Bruna Josef

Background: Organ transplantation (Tx) is the standard treatment for end-stage renal failure in diabetic patients. With an improvement in patient and graft survival, the bone loss and persistent abnormalities in bone metabolism are long-term complications to manage.Patients and methods: We investigated the prevalence of osteoporosis and osteopenia in 256 diabetic patients (142M, 114F) after the kidney and pancreas Tx for renal failure due to diabetic nep...

ea0011p617 | Neuroendocrinology and behaviour | ECE2006

The levels of ghrelin and leptin and body fat mass in patients treated for thyroid dysfunction

Brunova J , Karasova L , Kasalicky P

Introduction: Patients successfully treated for hyperthyroidism show often the excessive weight gain and patients with hypothyroidism seldom regain their premorbid weight despite satisfactory control of their thyroid function.Aim of study: We compared the levels of hormones of ghrelin and leptin in patients with hyper and hypothyroidism, treated and untreated. We aimed to find if they play a role in a new energy balance in these patients.<p class="ab...

ea0037ep1208 | Clinical Cases–Pituitary/Adrenal | ECE2015

Complicated investigation of adrenal incidentaloma in a critically ill patient – a case study

Kratochvilova Simona , Wohl Petr , Hoskova Lenka , Kettner Jiri , Vrbska Jana , Kudla Michal , Brunova Jana

Adrenal incidentaloma is frequently encountered in endocrinological praxis, however in specific situations the proper investigation is almost impossible. A 60-years old patient was admitted to our intensive care unit with a myocardial infarction in cardiogenic shock requiring ionotropic support and intraaortic balloon counterpulsation. On account of ejection fraction 15–20% an urgent pretransplantation investigation was started. Abdominal ultrasound displayed a hypoechoge...