Endocrine Abstracts

Introduction and Aim: Polycystic Ovary Syndrome (PCOS) is an endocrine disease closely related to several risk factors for cardiovascular disease. Previous study demonstrated an impaired cardiopulmonary functional capacity in PCOS women. The present study was performed to evaluate the effects of 3-months exercise training (ET) programme on cardiopulmonary functional capacity in young women with PCOS.Patients and Methods: The study was conducted according...

Introduction and aim: Polycystic Ovary Syndrome (PCOS) is a common disorder associated with a wide range of endocrine and metabolic abnormalities. Obesity is present in about 45–50% of PCOS women. Increased cardiovascular risk factors and evidence of subclinical cardiovascular disease (CVD) have been reported in PCOS. The aim of the present study was to evaluate whether visceral fat amount may be considered as predictor for early CVD in PCOS women.P...

The GH/IGF-I axis function are reported to ameliorate after weight-loss. Bariatric surgery leads to a significant weight loss in morbidly obese patients. We investigated the relationships between GH/IGF-I axis and body composition in 20 morbidly obese females (BMI: 44.8±4.7; waist circumference (W) 119.5±7.2 cm, age 33.7±11.7 yrs) with a normal glucose tolerance, before and after laparoscopic silicone adjustable-gastric banding (LASGB). The GH axis was evaluated...

Introduction and aim: Polycystic ovary syndrome (PCOS) is associated with an adverse metabolic and cardiovascular risk (CVR) profile, including: diabetes, insulin resistance, dyslipidemia and hypertension. Heart rate recovery (HRR) is a measure of autonomic dysfunction and an abnormal HRR is also associated with increased mortality. To date, no evaluation of autonomic function in young PCOS women has been performed, therefore the aim of the present study was to evaluate the HR...

The polycystic ovary syndrome (PCOS) is not only the first cause of female infertility but also a complex, endocrine, multifaceted disease with important health implications. PCOS is often associated to the metabolic syndrome, and insulin resistance represents the main characteristics for both these syndromes. The metabolic disturbances characteristic of insulin-resistant states have been linked to the role of mitochondrial function and in particular to the maximal oxygen cons...

Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases in women, affecting up to 10% of women in reproductive age. The evidence of polycystic ovaries at ultrasonography has been recently considered as a further criteria to diagnose PCOS. In order to determine whether FSH receptor gene affects hormonal and/or metabolic parameters of PCOS women the presence of FSH receptor gene mutations was investigated. Forthy women aged between 18 and 40 years with poly...