Endocrine Abstracts

Expressions of KISS-1 and GPR54 have been demonstrated in a variety of tissues, including pituitary. Given their role in reproduction and in gonadotrophin secretion, we examined the regulation of their expression by steroids and GnRH in the rat pituitary using real-time PCR procedure.After ovariectomy (OVX), pituitary KISS-1 mRNA levels dramatically decrease whereas GPR54 transcripts slightly increase compared with intact cycl...