Searchable abstracts of presentations at key conferences in endocrinology

ea0081p567 | Calcium and Bone | ECE2022

Remote management of osteoporosis in the first wave of the Covid-19 pandemic

Salvio Gianmaria , Gianfelice Claudio , Firmani Francesca , Lunetti Stefano , Ferroni Rossella , Balercia Giancarlo , Giacchetti Gilberta

We conducted a survey during the first pandemic wave of coronavirus disease 2019 (COVID-19) on a large group of osteoporotic patients to evaluate the general conditions of osteoporotic patients and the impact of the pandemic on the management of osteoporosis, finding high compliance to treatments and low COVID-19 lethality. In a telephone survey conducted from April to May 2020, patients from the Osteoporosis Center, Clinic of Endocrinology and Metabolic Diseases of Umberto I ...

ea0037ep66 | Adrenal cortex | ECE2015

Clinical significance of contralateral adrenal suppression during adrenal vein sampling in primary aldosteronism

Monticone Silvia , Satoh Fumitoshi , Viola Andrea , Fischer Eveline , Vonend Oliver , Bernini Giampaolo , Quinkler Marcus , Giacchetti Gilberta , Morimoto Ryo , Willemberg Holger , Maccario Mauro , Veglio Franco , Ito Sadayoshi , Reincke Martin , Mulatero Paolo

Objective: Adrenal vein sampling (AVS) is recognised by Endocrine Society guidelines as the only reliable mean to distinguish between aldosterone producing adenomas and bilateral adrenal hyperplasia, the two most common subtypes of primary aldosteronism (PA). However, AVS protocols are not standardised and vary between centres. The objective of the present study was to assess whether the presence or absence of contralateral adrenal (CL) suppression has an impact on the postope...

ea0016oc1.6 | Neuroendocrinology and pituitary | ECE2008

The metabolic effects of ghrelin and glucocorticoids are mediated by AMP-activated protein kinase (AMPK) and endogenous cannabinoids

Kola Blerina , Christ-Crain Mirjam , Farkas Imre , Wittmann Gabor , Lolli Francesca , Seboek Dalma , Harvey-White Judith , Kunos George , Muller Beat , Arnaldi Giorgio , Giacchetti Gilberta , Boscaro Marco , Grossman Ashley B , Fekete Csaba , Korbonits Marta

Ghrelin, cannabinoids and glucocorticoids have all orexigenic and widespread metabolic effects. AMPK is a major controller of many metabolic processes. We have studied the effects of ghrelin and glucocorticoids and their interaction with endocannabinoids using cannabinoid-receptor-1 (CB1) knock-out mice and CB1 antagonist-treated mice, and using tissue samples from patients with Cushing’s syndrome and from a rodent model of Cushing’s syndrome. AMPK activity and downs...

ea0014p211 | (1) | ECE2007

The metabolic changes induced by glucocorticoids: involvement of AMP-activated protein kinase

Christ-Crain Mirjam , Kola Blerina , Lolli Francesca , Fekete Csaba , Seboek Dalma , Wittman Gabor , Ajodha Sharon , Harvey-White Judith , Kunos George , Mueller Beat , Amaldi Giorgio , Giacchetti Gilberta , Boscaro Marco , Grossman Ashley , Korbonits Marta

Background: Excess glucocorticoids result in Cushing’s syndrome (CS) which is characterised by increased food intake, central obesity, dyslipidaemia and insulin resistance, leading to the metabolic syndrome. AMPK is a regulator of energy homeostasis and plays an important role in the regulation of appetite, glucose uptake, lipogenesis and gluconeogenesis. We hypothesised that the effects of corticosteroids on metabolism would be mediated by changes in AMPK activity in a t...

ea0013p166 | Diabetes, metabolism and cardiovascular | SFEBES2007

The effects of glucocorticoids on the expression of gluconeogenic and lipogenic enzymes in a rodent model of Cushing’s Syndrome

Christ-Crain Mirjam , Kola Blerina , Lolli Francesca , Fekete Csaba , Seboek Dalma , Wittman Gabor , Ajodha Sharon , Harvey-White Judith , Kunos George , Mueller Beat , Amaldi Giorgio , Giacchetti Gilberta , Boscaro Marco , Grossman Ashley , Korbonits Marta

This abstract was printed as a duplication of abstract P291 and corrected onlineBackground: Excess glucocorticoids result in Cushing’s syndrome (CS) which is characterised by increased food intake, central obesity, dyslipidaemia and insulin resistance, leading to the metabolic syndrome. AMPK is a regulator of energy homeostasis and plays an important role in the regulation of appetite, glucose uptake, lipogenesis and gluconeogenesis. We hypothesised...