Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1271 | Thyroid (non-cancer) | ECE2017

How does overt and subclinical hypothyroidism due to thyroiditis of Hashimoto affect lipid parameters

Tosheva Gergana , Siderova Mira , Hristozov Kiril , Bocheva Yana , Kostova Mila

Aim: The aim of this retrospective study is to assess the lipid disturbances in patients with autoimmune thyroiditis.Methods: 1380 patients with autoimmune thyroiditis, hospitalized in Endocrinology department of ‘St. Marina’ Hospital, Varna for the period of 2004–2015 year, participated in the study. After excluding conditions influencing lipid profile, 771 patients remained for analysis (36 men and 735 women, mean age 49.81±13.98 ye...

ea0011p706 | Reproduction | ECE2006

Functional characterization of the follicle-stimulating hormone receptor core promoter: applying a comparative approach among primates

Brune M , Kostova E , Nieschlag E , Gromoll J

Follicle-stimulating hormone (FSH) is essential for primate reproduction, acting via the FSH-receptor (FSHR) which is expressed in Sertoli and granulosa cells only. Despite its highly specific expression pattern, knowledge of the FSHR promoter and transcriptional regulation is still very limited. To gain insights into the regulatory elements controlling FSHR expression we characterized the core promoter activity of all important primate lineages including human. We isolated DN...