Searchable abstracts of presentations at key conferences in endocrinology

ea0085p55 | Diabetes 2 | BSPED2022

Recognising and raising safeguarding and child protection issues in childrens diabetes. Early findings from a qualitative study exploring specialist paediatric diabetes healthcare professionals’ experiences

Yardley Diana , Bekaert Sarah , Kozlowska Olga

Introduction: Managing diabetes in a child is complex and demanding for parents, for some families this is exacerbated by additional demands. Compromised family capacity may lead to diminished management of a child’s diabetes, increasing the risk for acute and long-term complications. The UK has the highest rates in Europe of children (0-14years) living with Type 1 diabetes (International Diabetes Federation, 2019) however, it is concerning that less than 40% have a HbA1c...

ea0041ep1131 | Thyroid cancer | ECE2016

Fine needle thyroid biopsy – time to change of indications?

Maciejewski Marek , Sawicka Agnieszka , Slomian Michal , Budzynska-Nosal Renata , Kozlowska Beata , Marczewski Krzysztof

Introduction: After a period of enthusiasm for the early detection of cancer, apparently we are entering a period of skepticism, questions and side effects in the form of unnecessary operations and their complications and costs. This also applies to thyroid cancer, and actually nodules and lesions visible only in ultrasoundMethod. Prospective observation of consecutive patients in one centre.Results: In Years 2013 and 2014 we have performed 2189 ultrasou...

ea0035p541 | Endocrine tumours and neoplasia | ECE2014

Efficiency of ultrasound-guided percutaneous thyroid nodule biopsy among patients hospitalized in the department of internal medicine

Maciejewski Marek , Kozlowska Beata , Budzynska-Nosal Renata , Sawicka Agnieszka , Slomian Michal , Marczewski Krzysztof

Introduction: Fine needle aspiration of thyroid nodules is the most frequently performed ambulatory and recommendations for its performance are quite accurately described in the national and international guidelines. However, there is always a need to analyze the effectiveness of such proceedings.The aim of this study was to analyze such effectiveness in group of hospitalized patients.Method: The reason for hospitalization in the v...

ea0029p174 | Bone & Osteoporosis | ICEECE2012

The assessment of the behavior of the interleukins IL1β and IL6 and bone mineral density (BMD) and bone metabolism (IBM) in women of postmenopausal age

Tryniszewski W. , Gorska-Chrzastek M. , Kozlowska M. , Gadzicki M. , Raciborska I. , Zajac A. , Maziarz Z.

Women’s bone metabolism is regulated by estrogens and interleukins. During the menopausal period the estrogens’ protective activity is decreased and the production of IL1β and IL6 is increased.The aim of the studyThe assessment of the dependency between IL1β i IL6 and estradiol values and BMD and IBM in postmenopausal women.Material: Forty-eight women, age 49–61, without menstruation ...

ea0011p249 | Cytokines and growth factors | ECE2006

Plasma interleukin 18 in patients with polycystic ovary syndrome – relation to insulin resistance

Kowalska I , Straczkowski M , Nikolajuk A , Kozlowska A , Karczewska-Kupczewska M , Adamska A , Wolczynski S , Kinalska I , Gorska M

Aim of the study: Polycystic ovary syndrome (PCOS) is common disease affecting women in reproductive age which leads to anovulation. In pathogenesis of PCOS insulin resistance plays an important role. The aim of the present study was to look for possible relationship between interleukin 18 (IL-18) and insulin resistance in patients with PCOS.Material and Methods: The study was done in 76 patients with PCOS and 40 women without menstrual disturbances. The...

ea0041ep406 | Diabetes (to include epidemiology, pathophysiology) | ECE2016

Decreasing betatrophin levels during pregnancy in healthy women

Zielinska Anna , Maciulewski Rafal , Siewko Katarzyna , Poplawska-Kita Anna , Kozlowska Gabryela , Lipinska Danuta , Gorska Maria , Szelachowska Malgorzata

Introduction and aims: To date we have had some evidence that betatrophin is associated with insulin resistance. Some studies have demonstrated that betatrophin levels are elevated in type 2 diabetes, obesity and gestational diabetes. It has been shown that in mice betatrophin significantly improves beta cell function and glucose tolerance. This is the first study on betatrophin in which pregnant women were observed during all trimesters and in postpartum period to evaluate it...

ea0041ep996 | Thyroid (non-cancer) | ECE2016

Transforming growth factor β1 in postpartum thyroiditis

Zielinska Anna , Maciulewski Rafal , Siewko Katarzyna , Poplawska-Kita Anna , Kozlowska Gabryela , Lipinska Danuta , Gorska Maria , Szelachowska Malgorzata

Introduction and aims: TGF-β1 participates in the pathogenesis of autoimmune diseases e.g. diabetes, Hashimoto disease, autoimmune digestive system disorders. The aim of our study was to evaluate TGF-β1 levels during pregnancy and after childbirth in women who developed postpartum thyroiditis (PPT) in comparison to the healthy control group (CG) and women with positive anti-thyroid antibodies (ATA+) who did not develop PPT.Material and method: ...

ea0016p531 | Obesity | ECE2008

Metabolic syndrome and endothelial dysfunction in women with polycystic ovary syndrome – relationship with insulin sensitivity

Kowalska Irina , Kozlowska Agnieszka , Straczkowski Marek , Karczewska-Kupczewska Monika , Adamska Agnieszka , Nikolajuk Agnieszka , Wolczynski Slawomir , Gorska Maria

Polycystic ovary syndrome (PCOS) is a main cause of women infertility. There are data suggesting an increased risk for cardiovascular disease in PCOS. Insulin resistance might play a role in the pathogenesis of PCOS and its metabolic complications. The aim of the study was to asses the prevalence of The National Cholesterol Education Program (NCEP)-defined metabolic syndrome (MS) in women with PCOS in relation to insulin resistance and endothelial dysfunction – soluble E-...