Searchable abstracts of presentations at key conferences in endocrinology

ea0038p245 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2015

Obstructive sleep apnoea and bariatric surgery: the need for more universal screening and post-operative follow up

Martinou Chrysiis , Nayak Ullal , Katreddy Mahesh , Varughese George , Varadhan Lakshminarayanan

Aim: Bariatric surgery can provide significant weight loss but a complete resolution obstructive sleep apnoea (OSA) cannot be predicted. The aim of our audit was to assess the prevalence of OSA in bariatric clinics and outcomes after malabsorptive bariatric surgery.Methods: Retrospective observational analysis was performed on patients who had undergone bariatric surgery (laparoscopic gastric bypass and sleeve gastrectomy) and completed a minimum of 6 mo...

ea0054is12 | (1) | NuclearReceptors2018

Nuclear receptor networks in male fertility

Martinot Emmanuelle , Sedes Lauriane , Baptissart Marine , Holota Helene , Angelique De Haze , Beaudoin Claude , Volle David H

Male fertility is controlled by complex interactions between hypothalamus, pituitary, and testis. The major functions of the testis include production of spermatozoa and synthesis of hormones. Testosterone is produced by the testicular Leydig cells and ensures male fertility. Testosterone is involved in the development of gonad, the attainment of puberty, the maintenance of secondary sexual characteristics as well as in spermatogenesis process. Many studies have highlighted th...

ea0038p203 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2015

Pre-operative assessment for Sleep apnoea in patients referred for bariatric surgery: the usefulness of various clinical screening tools

Martinou Chrysiis , Nayak Ullal , Varughese George , Thomas Ajit , Allen Martin , Varadhan Lakshminarayanan

Aim: Obstructive sleep apnoea (OSA) is widely prevalent in patients with obesity, referred for bariatric surgery. Various clinical tools are clinically used for screening pre-operatively before referring for formal sleep studies. The aim of our observational analysis was to assess the usefulness of various screening methods for OSA used in clinical practice.Methods: Records of all patients who had been referred to bariatric services in 2014 were reviewed...

ea0081p412 | Pituitary and Neuroendocrinology | ECE2022

Sodium alterations impair the long-term prognosis of hospitalized patients with COVID-19 pneumonia: hospital readmissions and mortality rates after a 18-month follow-up

Martino Marianna , Aboud Nairus , Perrone Michele , Falcioni Paolo , Giancola Giulia , Ciarloni Alessandro , Salvio Gianmaria , Silvetti Francesca , Taccaliti Augusto , Arnaldi Giorgio

Background: Dysnatremia is common in hospitalized patients, often worsening the prognosis in pneumopathies and critical illnesses, such as COVID-19. Here, hyponatremia is an indicator of pulmonary involvement, while hypernatremia is associated with worse assistance outcomes, particularly when resulting from an overcorrected hyponatremia. Longer hospitalizations, readmissions after discharge and higher short- and long-term mortality rates have been observed in acute patients ex...

ea0063s8.2 | Genderdysphoria - delayed puberty | ECE2019

Management of puberty in transgender adolescents

Cools Martine

Context: Childhood gender dysphoria, when not attenuating after the onset of puberty, is very likely to persist. The aim of puberty suppressing therapy in gender dysphoric adolescents is increasingly shifting from ‘buying time to reflect on the diagnosis’ towards ‘avoiding the development of secondary sexual characteristics while awaiting eligibility for cross-sex hormones’. Various treatment regimens are available to suppress or decrease the effects of end...

ea0073js6.3 | ESE/EndoERN Joint Session: Rare endocrine disorders. Improving diagnosis, management and awareness by strengthening patients and physician collaboration | ECE2021

Living with androgen insensitivity syndrome - Multidisciplinary care team and research

Cools Martine

Men and women who have AIS face a number of challenges. Based on research insights from the past two decades, management of this pleiotropic condition during childhood has totally changed. In this presentation, we will update endocrinologists who provide care for adults living with AIS about these changes, as they will, after transition, need to further counsel their patients and coordinate multidisciplinary care and surveillance of retained gonads in adulthood. Girls with com...

ea0090p294 | Adrenal and Cardiovascular Endocrinology | ECE2023

Relative adrenal insufficiency in liver cirrhosis: a common but often forgotten critical condition

Petkovic Tijana , Marina Ljiljana , Petkovic Dunja-Simona , Martinov Nestorov Jelena , Culafic Djordje , Jovanovic Jelena , Ivovic Miomira , Stefan Sojat Antoan , Antic Natalija , Saravinovska Kristina , Arizanovic Zorana , Vujovic Svetlana

Introduction: Relative adrenal insufficiency (RAI) is common in critically ill patients and is characterized by the normal adrenal reserve for homeostatic demands and inadequate cortisol response in acute stress situations. RAI can also occur in patients with liver cirrhosis, both compensated and decompensated. However, it is often forgotten and difficult to diagnose due to the overlap between clinical symptoms of adrenal insufficiency and decompensated liver disease. Also, hy...

ea0026p252 | Pituitary | ECE2011

Initial management and complications of Cushing disease (CD): a French multicenter study of 437 patients

Baudry C , Martinie M , Fathallah-Sahnoun M , Gatta-Cherifi B , Khalil R Bou , Guignat L , Gay E , Raverot G , Brue T , Tabarin A , Chabre O , Bertherat J

Introduction: CD is a rare disease. Our aim was to describe demographic and clinical characteristics together with initial management of patients with CD.Patients and methods: A retrospective analysis of 437 CD patients diagnosed between 1996 and 2009, followed in 5 tertiary centers (Bordeaux, Grenoble, Lyon, Marseille, Paris) was performed in the frame of the national program for rare diseases.Results: 347 (80%) were women. Mean a...

ea0035p1042 | Thyroid (non-cancer) | ECE2014

Antithyroid drug-induced agranulocytosis: experience of the French centers of Pharmacovigilance with a retrospective study of more than 200 cases

Andres Emmanuel , Weitten Thierry , Alt-Tebacher Martine

Objective: Agranulocytosis to the antithyroid drugs is a rare adverse drug effect exposure to potentially lethal infections. It is a public health problem with hyperthyroidism in nearly 1% of the French population. However, many uncertainties remain in the knowledge, understanding, prevention and management of this drug effect. In this work, we report the French experience through pharmacovigilance data.Materials and methods: This is a retrospective stud...

ea0032p149 | Calcium and Vitamin D metabolism | ECE2013

Persistent primary hyperparathyreoidism

Kotova Irina , Gadzyra Alexander , Alayev Dmitry , Martino Elena

Introduction: Achievement of stable normocalcemia (88–98.8%) is considered a criterium of efficiency of surgical operations for primary hyperparathyroidism (PHPT) (P.Goudet et al. 2001, Zeiger 1997). In 1–15% of cases, persistence of PHPT is noted (Mariani et al. 2003, Mariette et al. 1998).Description of methods: In 110 of 175 patients (aged 14–72 years), parathyroid adenoma was verified, in 57 – hyperplasi...