Searchable abstracts of presentations at key conferences in endocrinology

ea0011oc58 | ThyroidOC57 British Thyroid Association Award | ECE2006

Interleukin 1: the optimal cytokine target in thyroid associated ophthalmopathy?

Cawood TJ , Moriaty P , O’Farrelly C , O’Shea D

Introduction: Anti-cytokine therapy may be useful for the treatment of active thyroid associated ophthalmopathy (TAO). We aimed to establish the effects of selected cytokines on intercellular adhesion molecule 1 (ICAM1) expression and adipogenesis in orbital fibroblasts (OFs) from patients with and without TAO.Methods: Orbital tissue was taken during surgery from 5 patients with TAO and 5 control subjects. Primary cultures of OFs were established and sta...