Endocrine Abstracts

Mediators of inflammatory reaction are present at every stage of forming of atheromatous plaque, its proliferation and destabilization. Cytokines play a key role in regulation of intensity of chronic inflamatory reaction. We aimed at investigation if IL-4 and IFN-gamma are predictors of MACE in a group of patients with acute myocardial infarction (AMI).A total of 50 patients: 40 males and 10 females, aged 56±10 years (mean±S.D.),...

Cytokines play a role in cardiovascular diseases by inducing inflammation, cell proliferation and apoptosis. It is well known that activated macrophages are one of the main sources of inflammatory cytokines. Previous studies have shown that the cells found in the vascular wall produce various kind of cytokines which are involved in cardiovascular diseases. It has been reported that some cytokines (IL-6, IL-8) are increased in acute coronary syndrome. The results of some other ...