Searchable abstracts of presentations at key conferences in endocrinology

ea0032p191 | Cardiovascular Endocrinology & Lipid Metabolism | ECE2013

Pentraxin-3 as a more sensitive marker of coronary artery disease severity than C-reactive protein

Szkodzinski Janusz , Hudzik Bartosz , Danikiewicz Aleksander , Pietka-Rzycka Anna , Lekston Andrzej , Zubelewicz-Szkodzinska Barbara

Introduction: Pentraxin-3 (PTX3) is an acute-phase reactant that shares structural and functional homology with C-reactive protein (CRP). However, unlike CRP, which is synthesized mainly in the liver, PTX3 is produced at the site of inflammation. It has been suggested that PTX3 plays the same role in the periphery that CRP does in circulation. PTX3 may represent a rapid marker for local inflammation.Methods: Fifty three patients with stable coronary arte...

ea0014p17 | (1) | ECE2007

Does stress test influence Interleukin (IL)-2 and IL-8 concentration in serum patients with stable ischaemic heart disease?

Romanowski Wojciech , Szkodzinski Janusz , Kaszuba Andrzej , Blazelonis Adam , Muryn Zuzanna , Anna Pietka-Rzycka , Zubelewicz-Szkodzinska Barbara

Background: There is growing evidence that adhesion molecules, proinflammatory cells and cytokines play an important role in a variety of cardiac pathophysiological conditions; Cytokines are responsible for the modulation of immune and inflammatory processes. It has been suggested that cytokines such as IL-1, IL-2, IL-6, IL-10 and TNF alpha are important modulators of atherosclerotic effects with IL-2 and Interferon γ having a proinflammatory atherogenic effect and IL-8 a...

ea0014p18 | (1) | ECE2007

Concentration of inflammatory factors such as CRP (acute phase response protein) and Interleukin (IL)-6 in serum patients with stable ischemic heart disease during trimetazidine treatment

Szkodzinski Janusz , Szewczyk Marek , Romanowski Wojciech , Danikiewicz Aleksander , Muc-Wierzgon Malgorzata , Zubelewicz-Szkodzinska Barbara

Background: The patomechanism of developing ischemic heart disease (i.h.d.) is stenosis of coronary blood vessels with plaque placed on vascular endothelium built with monocytes/macrophages, foam cells, oxidized LDL, leukocytes, platelets and collagen. Atherosclerotic lesions are heavily infiltrated by cellular components associated with inflammation and influenced by other inflammatory factors. Trimetazidine, a clinically effective antianginal agent acts by optimizing cardiac...

ea0011p218 | Cytokines and growth factors | ECE2006

The role of IL-4 and IFN-gamma as prognostic factors of major adverse cardiac events in patients with ST-elevation myocardial infarction assigned primary percutaneous coronary intervention

Osuch M , Szygula-Jurkiewicz B , Szkodzinski J , Wojnicz R , Lekston A , Polonski L , Blazelonis A , Zubelewicz-Szkodzinska B

Mediators of inflammatory reaction are present at every stage of forming of atheromatous plaque, its proliferation and destabilization. Cytokines play a key role in regulation of intensity of chronic inflamatory reaction. We aimed at investigation if IL-4 and IFN-gamma are predictors of MACE in a group of patients with acute myocardial infarction (AMI).A total of 50 patients: 40 males and 10 females, aged 56±10 years (mean±S.D.),...

ea0011p221 | Cytokines and growth factors | ECE2006

Interleukin 6 and transforming growth factor beta1 concentration in serum in patients with coronary vessels restenosis

Blazelonis AB , Szkodzinski J , Romanowski W , Danikiewicz A , Gasior M , Polonski L , Kaszuba A , Muc-Wierzgon M , Zubelewicz-Szkodzinska B

Cytokines play a role in cardiovascular diseases by inducing inflammation, cell proliferation and apoptosis. It is well known that activated macrophages are one of the main sources of inflammatory cytokines. Previous studies have shown that the cells found in the vascular wall produce various kind of cytokines which are involved in cardiovascular diseases. It has been reported that some cytokines (IL-6, IL-8) are increased in acute coronary syndrome. The results of some other ...

ea0041ep677 | Female Reproduction | ECE2016

The influence of the body fat distribution on the selected biochemical parameters in a group of women with Polycystic Ovary Syndrome – preliminary report

Bronczyk-Puzon Anna , Nowak Justyna , Kulik-Kupka Karolina , Koszowska Aneta , Zubelewicz-Szkodzinska Barbara

Introduction: Polycystic Ovary Syndrome is usually accompanied by metabolic changes such as carbohydrate and lipid metabolism disorders and obesity.Aim: The aim of the study is to determine the impact of the deployment of body fat on selected biochemical parameters in women with Polycystic Ovarian Syndrome.Materials and methods: The study included a group of 45 women with diagnosed Polycystic Ovarian Syndrome based on the 2003 Rott...

ea0041ep678 | Female Reproduction | ECE2016

The influence of insulin resistance on selected anthropometric and biochemical parameters in women with Polycystic Ovary Syndrome- preliminary report

Bronczyk-Puzon Anna , Kulik-Kupka Karolina , Nowak Justyna , Koszowska Aneta , Zubelewicz-Szkodzinska Barbara

Introduction: Polycystic Ovary Syndrome is the most common recognized endocrinopathy in women. The syndrome is often accompanied by obesity and insulin resistance.Aim: The aim of the study was to assess the differences between the selected anthropometric and biochemical parameters in a group of women with insulin resistance and without insulin resistance.Materials and methods: The study included a group of 45 women diagnosed with P...

ea0041ep835 | Obesity | ECE2016

Correlation between selected anthropometric, biochemical parameters and CRP- reactive protein concentration among patients with endocrine disorders

Kulpok Agata , Nowak Justyna , Kulik-Kupka Karolina , Bronczyk-Puzon Anna , Koszowska Aneta , Zubelewicz-Szkodzinska Barbara

Introduction: Anthropometric studies are one of the methods, by means of which it is possible to assess patient’s nutritional status.Aim: The aim of this study was to assess the relationship between the selected anthropometric as well as biochemical parameters and CRP- reactive protein concentration among patients with endocrine disorders.Materials and methods: The studied group involved all patients hospitalized at the Endocr...

ea0037ep178 | Reproduction, endocrine disruptors and signalling | ECE2015

Visceral adiposity index – new anthropometric marker in women with polycystic ovary syndrome: preliminary reports

Bronczyk-Puzon Anna , Jagielski Pawel , Kulik-Kupka Karolina , Nowak Justyna , Koszowska Aneta , Zubelewicz-Szkodzinska Barbara

Introduction: Early detection of carbohydrate and fat metabolism disorders in women with polycystic ovary syndrome allows the early prevention of cardiovascular diseases and type II diabetes.Aim: The purpose of this study was to assess the selected metabolic indicators and anthropometric measurements in two groups of women: metabolically healthy polycystic ovary syndrome (MH-PCOS) and metabolically unhealthy PCOS (MU-PCOS).Material...

ea0037ep926 | Thyroid (non-cancer) | ECE2015

Usefulness of Body Adiposity Index % in comparison to body composition analyser parameters among patients with and without autoimmune thyroid diseases hospitalised on Endocrinology Department-preliminary report

Koszowska Aneta , Nowak Justyna , Puzon Anna Bronczyk , Kupka Karolina Kulik , Dittfeld Anna , Szkodzinska Barbara Zubelewicz

Introduction: Anthropometric parameters such like BMI aren’t suitable enough for each type of figure and leads to misinformation about body composition. Body Adiposity Index (BAI) is suggested as an alternative for BMI.Aim: The aim of the study was to compare the usefulness of BAI in context to body composition parameters.Materials and methods: The BAI index was calculated for 86 patients according to previously described form...