Searchable abstracts of presentations at key conferences in endocrinology

ea0008p78 | Reproduction | SFE2004

Androgens inhibit atresia and retard early development of ovarian follicles: a model for PCOS?

Qureshi AI , Bano G , Whitehead S , Nussey SS , Mason HD

BackgroundPCOS is the commonest endocrinopathy in women. PCO are typified by increased ovarian follicles. The aetiology is unknown, but may be due either to enhanced follicular growth, reduced atresia, or both. Hyperandrogenism is almost universal either clinically or biochemically and in primates and sheep androgen excess in-utero produces ovaries phenotypically identical to those in PCOS. There have been no analyses of the effects of androgens on early...

ea0011p109 | Clinical case reports | ECE2006

A complex case of pregnancy and pegvisamont treated acromegaly

Qureshi AI , Ramanathan G , Walton A , Seal L , Bano G , Manyonda I , Panahloo A

A 29-year-old woman with polycystic ovary syndrome was diagnosed with acromegaly having presented with a two year history of secondary amenorrhea, a change in physical appearance and sweating. The diagnosis was confirmed with an oral glucose tolerance test that also demonstrated she had impaired glucose tolerance. Radiological imaging demonstrated a 2.2 cm pituitary tumor that was compressing the optic chiasm and a bi-temporal visual field defect was confirmed on Goldman field...