Searchable abstracts of presentations at key conferences in endocrinology

ea0035p593 | Endocrine tumours and neoplasia | ECE2014

IGF1 gene polymorphism and thyroid cancer

Soyluk Ozlem , Aral Ferihan , Boztepe Harika , Kapran Yersu , Erbil Yesim , Ustek Duran , Abaci Neslihan , Colak Nese

Aim: Several studies suggested that there is a relationship between serum levels of IGF1 or their polymorhisms and some cancer types. The genetic polymorphism in the region of IGF promoter region which is composed of cytosine┬ľadenine repeats, affects the promoter activity. It is suggested that serum IGF1 levels are inversely associated with the length of CA repeats. There are studies reporting that the carriers of the CA 19 allele are more likely to develop some cancer ty...

ea0016s30.4 | Clinical highlights | ECE2008

Evaluation of endothelial function and endothelial nitric oxide synthase intron 4a/b polymorphism in primary hyperparathyroidism

Ekmekci Ahmet , Abaci Neslihan , Agayev Ayaz , Aksakal Nihat , Oflaz Huseyin , Unaltuna Nihan Erginel , Erbil Yesim , Ozbey Nese Colak

The aim of this study is to evaluate endothelial function in patients with primary hyperparathyroidism (pHT) during the preoperative hypercalcemic and postoperative normocalcemic periods and to determine whether intron 4a/b polymorphism of eNOS gene influences endothelial function. Forty-one patients with pHT (28 women, 12 men; age: 48.4±11.6 years, serum calcium: 11.4±1.0 mg/dl, parathyroid hormone: 373.3±394.5 pg/ml) who fulfilled the criteria for parathyroid ...