Searchable abstracts of presentations at key conferences in endocrinology

ea0020p97 | Thyroid | ECE2009

Frequency of metabolic syndrome in hypothyroid patients

Ganidagli Sencer , Erdogan Mehmet , Kosenli Aybike , Kulaksizoglu Mustafa , Solmaz Soner , Sokmen Nebi , Canataroglu Abdullah

Objective: One of the common features of hypothyroidism is weight gain or failure to lose weight. Also bradycardia and mild hypertension can be seen. Impact of thyroid hormone deficiency on glucose and insulin metabolism is not fully understood. Thyroid hormones play role in lipid synthesis, metabolism and mobilization. Metabolic syndrome is a state which most features of hypothyroidism can be seen. Our aim is to investigate the frequency of metabolic syndrome in hypothyroid p...

ea0020p140 | Thyroid | ECE2009

Anemia frequency and etiology in primary hypothyroidism

Kosenli Aybike , Erdogan Mehmet , Ganidagli Sencer , Kulaksizoglu Mustafa , Solmaz Soner , Kosenli Ozgun , Unsal Cagatay , Canataroglu Abdullah

Objective: Thyroid hormones directly or indirectly, through erythropoietin, stimulate growth of erythroid colonies. Anemia is often the first sign of hypothyroidism. Hypothyroidism can lead to a wide variety (%20–60) of anemic disorders. Numerous mechanisms are involved in the pathogenesis of these anemias which can be microcytic, macrocytic and normocytic. Microcytic anemia is usually ascribed to malabsorption of iron and loss of iron by menorrhagia. Macrocytic anemia is...

ea0020p373 | Diabetes and Cardiovascular | ECE2009

Hyperhomocysteinemia may be a risk factor for diabetic foot ulcer development

Solmaz Soner , Erdogan Mehmet , Kulaksizoglu Mustafa , Ganidagli Sencer , Kosenli Aybike , Sakalli Hakan , Canataroglu Abdullah

Background: Diabetic foot ulcer and lower extremity amputation are leading causes of mortality and morbidity in diabetic patients. Diabetic neuropathy and peripheral vascular disease are major reasons for diabetic foot ulcer. Most of the studies showed that hyperhomocystinemia is related with microvascular and macrovascular complications in diabetic patients. Also hyperhomocysteinemia is related to poor ulcer healing. In this study, we investigated the relationship of hyperhom...

ea0020p387 | Diabetes and Cardiovascular | ECE2009

Plasma thrombin-activatable fibrinolysis inhibitor (TAFI) antigen levels in diabetic foot ulcers

Erdogan Mehmet , Solmaz Soner , Canataroglu Abdullah , Kulaksizoglu Mustafa , Cetinkalp Sevki , Ozgen Gokhan , Saygili Fusun , Yilmaz Candeger

Objective: Diabetic foot ulcer is associated with increased morbidity and mortality. The most important factor related to the development of foot ulcer is peripheral neuropathy. Thrombin-activatable fibrinolysis inhibitor (TAFI) is associated with coagulation, fibrinolysis and inflammation. Plasma TAFI may participate in arterial thrombosis in cardiovascular diseases (CVD). TAFI may be involved in the mechanism of vascular endothelial damage in diabetic patients. The aim of th...