Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep69 | Adrenal and Cardiovascular Endocrinology | ECE2022

Epidemiological and clinical data and factors of poor blood pressure control in known hypertensive patients in the Sfax region

Mkaouar Fatma , Mnif Fatma , Boujelben Khouloud , Jdidi Jihen , Abid Mohamed

Introduction: Hypertension is a very common chronic disease worldwide. Its imbalance is one of the main causes of cardiovascular and neurodegenerative complications.Patients and Methods: We collected data from hypertensive patients who voluntarily presented for screening on both diabetes and hypertension screening days.Poor blood pressure control was defined as systolic blood pressure (SBP) greater than or equal to 140 mmHg and/or diastolic blood pressur...

ea0049ep667 | Obesity | ECE2017

Obesity and infertility among Tunisian women of reproductive age: about 40 cases

Hadjkacem Faten , Rebai Mariem , Saidane Dalila , Ghorbel Dorra , Abid Mohamed

Obesity is on the increase worldwide and mainly in women of reproductive age. In turn, it is associated with various reproductive complications. To assess the detrimental effect of obesity on reproductive health and the means of its management, this retrospective cohort study of 40 obese and infertile women has been conducted in the department of endocrinology and diabetology of Hedi Chaker hospital in Sfax-Tunisia from 2009 to 2014. These patients have a mean age of 34 years ...

ea0056p343 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Nutrition of non-fasting patients with diabetes during the month of Ramadan

Lassoued Najoua , Abid Neila , HadjKacem Faten , Charfi Nadia , Abid Mohamed

Introduction: Fasting during the month of Ramadan is the most observed religious practice by Muslims. Diabetes is one of the condition that exempt Muslims from fasting because of the risk of complications. The International Diabetes Federation states that high-risk patients ‘should not fast’. The objective of this study was therefore to evaluate the daily food intake during the month of Ramadan in non-fasting patients with diabetes in order to detect diet mistakes ma...

ea0063gp29 | Diabetes and Cardiovascular Disease | ECE2019

Systematic screening of masked hypertension in normotensive type 2 diabetic patients

Ghorbel Dorra , Hadjkacem Faten , Triki Faten , Mnif Mouna , Charfi Nadia , Rekik Nabila , Kammoun Samir , Abid Mohamed

Introduction: Masked hypertension (MH) is a relatively recent description leading to a similar cardiovascular risk as permanent hypertension. Masked hypertension is more common among diabetic patients.Methods: This was a case-control study. We performed 24-hour ambulatory BP in 53 type 2 diabetic patients normotensive in clinical measurement. We compared both Masked Hypertension and Normotensive groups according to clinical/laboratory parameters and targ...

ea0063p805 | Thyroid 2 | ECE2019

Predisposition to autoimmune thyroid diseases within a Tunisian multiplex family

Chabchoub Ghazi , Sefi Wajdi , Charfi Nadia , Kacem Faten Hadj , Mnif Mouna , Keskes Leila , Abid Mohamed

Autoimmune thyroid disease (AITD), including Graves’ disease (GD) and Hashimoto’s thyroiditis (HT), is caused by multiple genetic and environmental factors. The clinical and immunological features of GD and HT are distinct; however, there are multiplex families with both GD and HT. In order to study the genetic susceptibility factors to AITDs, we have followed up 115 control members belonging to a large Tunisian family with a high prevalence of AITDs (Akr family) dur...

ea0063p987 | Diabetes, Obesity and Metabolism 3 | ECE2019

Epidemiological, clinical and biochemical characteristics of metabolic syndrome in adults living in South of Tunisia

Chabchoub Ghazi , Gargouri Imene , Kacem Faten Hadj , Charfi Nadia , Mnif Mouna , Keskes Leila , Abid Mohamed

The metabolic syndrome (MetS) is a constellation of physiological and biochemical abnormalities characterized by obesity, hyperglycaemia, elevated triglycerides and decreases in high density lipoprotein cholesterol (HDL-C), and hypertension. The MetS promotes atherosclerosis, and increases the risk of developing diabetes and cardiovascular disease (CVD), as well as rates of mortality. Thus, it has become one of the major public health challenges worldwide. In Tunisia, few stud...

ea0063p1031 | Interdisciplinary Endocrinology 2 | ECE2019

Acid sphingomyelinase deficiency unusually associated with severe delay of growth

Naifar Manel , Kallel Faten , HadjKacem Faten , Messoud Olfa , Messedi Sondes , Abid Mohamed , Ayedi Fatma

Background: Acid Sphingomyelinase Deficiency (ASMD) is a rare lysosomal storage disease caused by mutations in the SMPD1 gene. Typically, the p.Arg610del homozygotes had normal linear growth.Case report: We reported the cases of 2 Tunisian brothers aged 23 and 13 years respectively, who have been admitted for splenomegaly and polyadenopathies. Physical examination showed pubertal and growth delay for both cases. Biological evaluation showed mode...

ea0063p1058 | Pituitary and Neuroendocrinology 3 | ECE2019

Pituitary apoplexy: diagnosis, management and outcome in 44 patients

Gargouri Imen , Hadjkacem Faten , Mnif Mouna , Walha Mohamed , Rekik Nabila , Charfi Nadia , Ayadi Fatma , Abid Mohamed

Introduction: Pituitary apoplexy (PA) is a rare incident defined by the occurrence of necrosis and/or haemorrhage of the pituitary gland. PA is a clinical syndrome characterized by the sudden onset of headache, vomiting, visual impairment and decreased consciousness in some cases. The objectives of our study are to describe its clinical, biological and imaging features as well as the management of PA in the region of Sfax.Patients and methods: It is a re...

ea0063p1213 | Thyroid 3 | ECE2019

Hyperthyroidism and hepatic dysfunction: the impact of congestive heart failure

Benothman Wafa , Kacem Faten Hadj , Gargouri Imen , Elleuch Mouna , Mnif Fatma , Abid Mohamed

Introduction: Hyperthyroidism (HT) has been associated with hepatic dysfunction in the presence or absence of congestive heart failure (CHF). Our objective is to study the correlation between the clinical and biological presentation of hepatic abnormalities and the cardiac status.Patients and methods: This retrospective study included 17 patients hospitalized in the endocrinology department of Hedi Chaker Hospital in Sfax over 20 years (1997–2017). ...

ea0063ep102 | Pituitary and Neuroendocrinology | ECE2019

Thyrotropin-producing pituitary adenoma: 3 case reports

Hadjkacem Faten , Gargouri Imen , Bensalah Dhouha , Neifar Manel , Boujelben Khouloud , Charfi Nadia , Rekik Nabila , Abid Mohamed

Introduction: Thyrotropin-secreting pituitary adenomas represent less than 1% of all pituitary adenomas. Usually, patients present mild or moderate signs of hyperthyroidism and Hormonal evaluation shows increased free thyroid hormone concentration with detectable, normal or increased serum thyrotropin (TSH) level. Herein we report three cases of thyrotropin adenomas with particular clinical and biological features.Observations: Three patients, aged 25 38...