Searchable abstracts of presentations at key conferences in endocrinology

ea0017p44 | (1) | BSPED2008

Clinical challenges in children with Type I diabetes mellitus aged less than 6 years old in a UK region

Anderson Y , De Palma A , Widmer B , Ong K , Acerini C

Objectives: To assess current clinical practice in children aged 0–5.99 years with Type I Diabetes Mellitus (T1DM).Methods: All paediatric diabetes centres (n=17) within a single UK region were asked to provide retrospective data for the year ending 01/12/07. 15 (88%) centres responded and provided data for each child on presentation, initial and current insulin regimens. Outcome measures were HbA1c, and acute hospital admissions post-diagnos...

ea0005p253 | Steroids | BES2003

Assessment of antiandrogenic activity in a range of environmental contaminants

Jones E , Martin H , Acerini C , Hughes I

Hormonal activation of the androgen receptor plays a critical role in male fetal sex differentiation.Current hypotheses concerning estrogen/androgen balance and the role of estrogenic environmental contaminants have led us to investigate the capacity for androgenic/antiandrogenic activity in such chemicals. We have previously developed a sensitive in vitro assay using a telomerase-immortalised human cell line capable of detecting putative endocrine disrupting activi...

ea0024oc2.8 | Oral Communications 2 (Brief Communications) | BSPED2010

Radio-iodine therapy for autoimmune hyperthyroidism. A two centre, retrospective evaluation of practice and outcomes

Wnuk W , Balan K K , Cheetham T D , Acerini C L

Radio-iodine (I131) (RI) is regarded as an effective therapy for patients with autoimmune hyperthyroidism (AH). Treatment protocols and outcomes are well defined in adult endocrinology practice but not for children and adolescents where RI is now considered a safe therapy option after relapse following anti-thyroid drugs (ATD). We retrospectively evaluated the use of RI in 36 patients (6M) with AH from 2 regional units located in the North and East of England. Data ...