Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep1121 | Thyroid cancer | ECE2016

One thyroid, three tumors within: a case of three collision tumors

Selalmatzidou Despoina , Adamidou Fotini , Mintziori Gesthimani

Introduction: Collision tumors of the thyroid are neoplasms of distinct histology located within the same gland. Although rare, the most commonly described collision tumors of thyroid origin are medullary and papillary carcinomas. We describe a case of co-existence of a benign follicular adenoma in a dominant nodule with a micropapillary and a micromedullary carcinoma in a patient carrying a heterozygous germline RET polymorphism.Case report: A 74-year-o...

ea0063p851 | Adrenal and Neuroendocrine Tumours 3 | ECE2019

True silent pheochromocytoma: description of a rare entity

Adamidou Fotini , Komzia Paraskevi , Mpatsi Ourania , Georgiou Thomas , Kita Marina

Introduction: With the advent of modern imaging, up to 30% of adrenal pheochromocytomas are discovered incidentally in asymptomatic patients. Smaller tumors may be ‘pre-biochemical’ in their secretory capacity, but truly nonfunctioning tumors over 3 cm are exceedingly rare. We describe a case of a clinically and biochemically silent pheochromocytoma.Case report: A 65-year-old woman was found to have a left adrenal incidentaloma on an abdominal ...

ea0063p1163 | Thyroid 3 | ECE2019

Atypical hyperthyroidism in a case of neutrophilic dermatosis (Sweet’s syndrome)

Adamidou Fotini , Komzia Paraskevi , Georgiou Thomas , Kita Marina

Introduction: Sweet’s syndrome is a rare, acute febrile neutrophilic dermatosis, associated with a variety of inflammatory and neoplastic conditions, drug reactions and rarely with a spectrum of thyroid dysfunction. A possible link between thyroid autoimmunity and Sweet’s syndrome has been previously suggested by rare reports of Hashimoto’s thyroiditis, subacute thyroiditis and classic Graves’ disease. We describe a case of ‘atypical’ hyperthyroid...

ea0049gp40 | Bone & Calcium Homeostasis 1 | ECE2017

Coexistence of primary hyperparathyroidism with papillary thyroid carcinoma: a case series

Anagnostis Panagiotis , Panagiotou Athanasios , Adamidou Fotini , Rafailidis Savvas , Kita Marina

Introduction: Primary hyperparathyroidism (PHPT) may rarely coexist with non-medullary thyroid carcinoma (NMTC). We report the clinical manifestation and management of nine cases of synchronous PH and NMTC.Cases: Eight women and one man were included (mean age at diagnosis: 64±6.6 years). In all cases, PH was the initial diagnosis, whereas NMTC was detected incidentally, after ultrasound assessment for PH. The histological diagnosis of NMTC was clas...

ea0049ep771 | Clinical case reports - Thyroid/Others | ECE2017

Incidental asplenia in a patient with presumed type 2 autoimmune polyglandular syndrome (APS-2): misclassification or overlap?

Georgiou Thomas , Adamidou Fotini , Mintziori Gesthimani , Kita Marina

Introduction: Asplenia has been reported in 10% of patients with type 1 APS (APS-1), but has never been reported in APS-2. We describe a patient with presumed APS-2 and aplenia.Case report: A 69-year-old woman was diagnosed with B12 deficiency with severe anemia at age 21 and insulin dependent diabetes mellitus at age 33, following routine testing. At 59, she was hospitalized with salt wasting and a diagnosis of Addison’s disease was made, which was...

ea0049ep827 | Thyroid (non-cancer) | ECE2017

Orbital disease primer for Endocrinologists-not always thyroid associated orbitopathy (TAO): a case vignette

Adamidou Fotini , Manani Christina , Anagnostis Panagiotis , Georgiou Thomas , Boboridis Kostas

Background: TAO is a rare disease, seriously involving 5% of patients with autoimmune thyroid disease. The clinical presentation may be difficult to distinguish from other orbital conditions.Case 1: A 63-year-old woman was admitted to the Neurology Service for worsening diplopia over the previous six months, with a working diagnosis of myasthenia gravis or multiple sclerosis. The Endocrine Service was consulted because of a long history of Hashimoto&#146...

ea0041ep44 | Adrenal cortex (to include Cushing's) | ECE2016

A microdeletion of PRKARIA associated with Carney complex

Adamidou Fotini , Mintziori Gesthimani , Lyssikatos Charalampos , Stratakis Constantine

Background: Carney complex (CNC) is a rare multiple neoplasia syndrome, its commonest endocrine manifestation being ACTH-independent Cushing’s syndrome, histologically characterized by primary pigmented nodular adrenocortical disease (PPNAD). There is significant genetic and phenotypic heterogeneity, but deletions at 17q24.2 are rare. We describe the particular characteristics of a patient with a microdeletion in this area.Case report: A 37-year-old...

ea0041ep57 | Adrenal cortex (to include Cushing's) | ECE2016

Testosterone and cortisol co-secretion by an adrenocortical adenoma presenting as secondary polycythemia

Adamidou Fotini , Mintziori Gesthimani , Vlahaki Efthymia , Kambaroudis Apostolos

Background: Androgen co-secretion in patients with adrenal Cushing’s syndrome is considered a marker of malignancy. Mixed secretion by benign adrenocortical tumors is rare. We describe a case of a middle aged woman presenting with Cushing’s syndrome and polycythemia.Case report: A 57-year-old lady was referred by the Hematology Service to our Endocrine Clinic for evaluation of an adrenal mass found in an abdominal CT in the course of investigat...

ea0041ep1154 | Thyroid cancer | ECE2016

Collision thyroid tumors among patients diagnosed with thyroid carcinomas

Mintziori Gesthimani , Adamidou Fotini , Selalmatzidou Despoina , Kita Marina

Introduction: Collision thyroid tumors are defined as independent and histologically distinct tumors that coexist within the thyroid gland. Collision thyroid tumors are rare and their prevalence is unknown.Methods: A retrospective, registry-based study was performed by reviewing the electronic medical records of the Department of Endocrinology, Ippokratio General Hospital of Thessaloniki, Greece. All patients with thyroidectomy and thyroid cancer diagnos...

ea0035p167 | Calcium and Vitamin D metabolism | ECE2014

Unusual case of intrathyroid parathyroid hyperplasia revealed by parathyroid hormone determination in fine-needle aspirate, co-existing with multifocal papillary thyroid carcinoma

Anagnostis Panagiotis , Karras Spyridon , Adamidou Fotini , Christoforidou Varvara , Cox Jeremy

Introduction: Ectopic parathyroid tissue is a rare cause of primary hyperparathyroidism (PHPT). Intrathyroid location has been reported in 18–33% of cases.Case report: A 67-year-old Caucasian female was admitted for evaluation of multi-nodular goiter and normocalcaemic PHPT. The patient was asymptomatic; her medical history was remarkable for hypertension, dyslipidaemia, and albuminuria. Her family history has positive for albuminuria.<p class="...