Endocrine Abstracts

Background: Graves’ disease (GD) is an auto-immune condition where the thyroid gland produces excess hormones due to stimulation of the TSH receptor. Treatments for GD have largely remained unchanged for over 60 years. The commonest treatment strategy is to use anti-thyroid drugs (ATD) which has limited efficacy and may have serious side-effects. Newer therapies are required that will supplement existing therapies and impact on the underlying immune mechanisms of GD. Vita...

Background: There is little information regarding the natural history of subclinical hyperthyroidism (SH) due to Graves’ disease (GD). The objectives of this study were to assess the natural course of individuals with SH due to GD over a prolonged period. We also investigated the factors contributing to the progression or remission in these patients.Methods: A prospective analysis of patients with SH due to GD between 2007 and 2013 who had at least ...