Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep952 | Pituitary - Clinical | ECE2016

A case of post-traumatic ACTH deficiency followed by Cushing syndrome prediagnosis

Gorar Suheyla , Ademoglu Esra Nur , Dolu Suleyman , Uyar Seyit

Pitüitary ACTH deficiency is one cause of secondary adrenal insufficiency. Genetic factors, autoimmunity, infiltrative disease, cranial trauma can cause ACTH deficiency. Hyperpigmented skin lesions are expected in primary adrenal insufficiency while they are very rare in secondary adrenal insufficiency. Striae are characterized by linear smooth bands of atrophic appearing skin. They are mostly associated with obesity, pregnancy, hypercortisolism/Cushing syndrome. Striae a...

ea0041ep1029 | Thyroid (non-cancer) | ECE2016

Increased levels of bisphenol a in euthyroid autoimmun thyroiditis

Ademoglu Esra , Keskin Muge , Gorar Suheyla , Carlioglu Ayse

Introduction: Autoimmune thyroiditis (AIT), also called Hashimoto thyroiditis or chronic lymphocytic thyroiditis is characterized by destruction of the thyroid gland involving apoptosis of thyroid epithelial cells. It usually presents as euthyroidism or subclinically hypothyroidism, rarely as overt hypothyroidism. The cause of HashimotoÂ’s thyroiditis is thought to be a combination of genetic susceptibility and environmental factors. Bisphenol A (BPA), an endocrine-disrupt...

ea0041ep629 | Endocrine tumours and neoplasia | ECE2016

Circulating levels of survivin in acromegaly

Ademoglu Esra , Candan Zehra , Gorar Suheyla , Niyazoglu Mutlu , Carlioglu Ayse , Yildiz Faruk , Baydar Idris , Sevimli Hakan , Arslan Abdulmuttalib

Introduction: Acromegaly is a chronic disorder characterized by chronic growth hormone (GH) excess. In most of cases, GH hypersecretion is derived from somatotroph cell tumors. Survivin is a member of apoptosis protein family, which was recently showed to be expressed in different benign and malignant human tumors. A number of studies showed overexpression of survivin in pituitary adenomas. This study is intended to determine circulating levels of survivin in patients with acr...

ea0022p53 | Adrenal | ECE2010

Primary bilateral adrenal lymphoma without adrenal insufficiency: a case report

Culha Cavit , Uc Ziynet Alphan , Ademoglu Esra Nur , Yildirim Ahmet , Dellal Dilek , Gorar Suheyla , Koc Gonul , Aral Yalcin

Although adrenal gland involvement may be seen in patients with diffuse (non-Hodgkin) lymphoma, primary adrenal lymphoma is quite rare and adrenal insufficiency accompanies the clinical picture in 2/3 of cases.Case: A 70-year-old male patient presenting with anorexia and weight loss was referred to our clinic for bilateral adrenal masses, which were detected by abdominal computerized tomography (CT) as 5.2×5.2×2.7 cm in the right adrenal and 11...

ea0041ep181 | Calcium and Vitamin D metabolism | ECE2016

Mean platelet volume in a patient with hypoparathyroidism: the relationship between metabolic syndrome, impaired fasting glucose and cardiovascular risk

Cipil Handan , Timur Ozge , Sevimli Hakan , Yildiz Faruk , Utlu Mustafa , Arslan Abdulmuttalip , Ademoglu Esra Nur , Budak Mehmet Emin , Baydar Idris , Kadi Melek , Carlioglu Ayse

Background: Parathyroid hormone (PTH) is a key regulator of mineral metabolism, the homeostasis of calcium, phospate, vitamin D and bone turnover. Hypoparathyroidism is a rare disease characterized by hypocalceamia with inappropriately low plasma levels of PTH. Mean platelet volume (MPV) is the measure of platelet size. Increased MPV has been associated with cardiovascular risk.Objective: In our preliminary study, we aim to show that untreated hypoparath...

ea0041ep524 | Diabetes complications | ECE2016

Is there a tendency for thrombosis in gestational diabetes mellitus?

Gorar Suheyla , Alioglu Bulent , Ademoglu Esra Nur , Uyar Seyit , Bekdemir Handan , Candan Zehra , Saglam Beylan , Koc Gonul , Culha Cavit , Aral Yalcin

Aims: Impact of gestational diabetes mellitus on the coagulation system, dynamics involved at a pathophysiological level and the exact mechanism remain unclear.To evaluate association between diabetes-related parameters and haemostatic factors in order to search for a tendency of thrombosis in gestational diabetes mellitus.Methods and Material: Nineteen pregnant women who had gestational diabetes mellitus, 16 healthy pregnant and 1...

ea0041ep696 | Female Reproduction | ECE2016

Increased uric acid levels and clinical relationship in polycystic ovary syndrome

Keskin Havva , Timur Ozge , Kaya Yasemin , Utlu Mustafa , Yildiz Faruk , Ademoglu Esra Nur , Kadi Melek , Budak Mehmet Emin , Gozcu Hakan , Sevimli Hakan , Durmaz Senay , Carlioglu Ayse , Kamalak Zeynep

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder that affects women of reproductive age. Clinical and biochemical characteristics are similar to metabolic syndrome. Insulin resistance in patients with metabolic syndrome, is associated with serum uric acid levels. In our study, we aimed to investigate the relationship between serum uric acid levels and clinical and laboratory in PCOS patients.Materials and Method: PCOS ...

ea0041ep788 | Obesity | ECE2016

Mean platelet volume in a patient with celiac disease: the relationship between metabolic syndrome, impaired fasting glucose and cardiovascular risk

Cipil Handan , Baydar Idris , Altinkaynak Konca , Ademoglu Esra , Laloglu Esra , Filiz Murat , Sanibas Ahmet Veli , Yildiz Faruk , Sevimli Hakan , Arslan Muttalip , Arikan Senay , Carlioglu Ayse

Celiac Disease (CD) is a chronic inflammatory disorder and requires life-long treatment and follow-up. Mean platelet volume (MPV), determinant of platelet function, is an independent risk factor for cardiovascular disease (CVD). Metabolic syndrome (MS) is a multiplex risk factor that arises from insulin resistance accompanying abnormal adipose deposition and function. It is a risk factor for coronary heart disease, as well as for diabetes, fatty liver, and several cancers....

ea0041ep1028 | Thyroid (non-cancer) | ECE2016

Is the high mean platelet volume associated with inflammation in subacute thyroiditis?

Simsek Eda , Yildiz Faruk , Ademoglu Esra , Durmaz Senay Arikan , Filiz Murat , Bingol Fatih , Bingol Buket , Baykan Emine Kartal , Aydin Unsal , Sanibas Ahmet Veli , Carlioglu Ayse

Introduction and aims: Subacute thyroiditis (ST) is a spontaneous remitting inflammatory disease of thyroid gland. Although there is no clear evidence for its specific etiology, multiple factors may responsible for this inflammatory reaction. Mean platelet volume (MPV) is a new important inflammatory marker that indicates disease activity. Aim of this study is to evaluate MPV value in patients with subacute thyroiditis.Materials and methods: Thirty-one p...

ea0035p115 | Calcium and Vitamin D metabolism | ECE2014

Correlations of vitamin D level with hormonal and biochemical parameters in polycystic ovary syndrome

Kucur Suna Kabil , Gozukara Ilay , Yilmaz Havva , Aksoy Aysenur , Uludag Eda Ulku , Uzkeser Hulya , Kaya Yasemin , Ademoglu Esra , Carlioglu Ayse , Durmaz Senay Arikan

Objective: To investigate the level of 25(OH) vitamin D (25(OH)D) and correlation between 25(OH)D level and hormonal-biochemical parameters in polycystic ovary syndrome (PCOS).Materials and methods: Thirty-three patients diagnosed with PCOS and 42 age and BMI matched control group admitted to Erzurumm Regional Training and Research Hospital from May to October were included in the study. Serum total testosterone (TT), free testosterone (fT), 25(OH)D, DHE...