ea0094p235 | Neuroendocrinology and Pituitary | SFEBES2023
Agan Shalom
, Areloegbe Stephanie
, Bashir Al-Amin
, Olaniyi Kehinde
Background of Study: Polycystic ovarian syndrome (PCOS) is an endocrine disorder, contributing to increased neurodegenerative disorders including hypothalamic disturbance. Short chain fatty acid (SCFA) has been reported to regulate metabolic health. However, its therapeutic nature in hypothalamic dysfunction, especially in PCOS individuals is unknown. This study hypothesized that SCFA reverses hypothalamic injury and its related abnormalities in experimentally...