Endocrine Abstracts

Optimal in-patient glycaemic control improves morbidity and mortality in in-patients with diabetes1. The National Inpatient Diabetes Audit (NaDIA) is an annual snapshot audit of diabetes inpatient care in England and in Wales. We performed a similar audit in Our Lady of Lourdes Hospital, Drogheda (OLOLHD, 363 in-patient beds) on 26/01/2022 and 08/10/2020. Data from all adult in-patients with diabetes were gathered using a standard proforma. Data from the OLOLHD 2022...

: In community-dwelling men, salivary testosterone (Sal-T) concentrations are thought to represent tissue hormone levels and correlate strongly with serum free-T levels. Measurement of salivary glucocorticoid concentrations is a non-invasive and objective means of assessing cortisol exposure in users and non-users of hydrocortisone therapy. We assessed relationships of Sal-T with transdermal testosterone replacement therapy (TD-TRT) and with markers of testosterone exposure. I...

Background: Many antipsychotics are obesogenic and contribute to significant weight gain with serious implications on patients’ physical and mental well-being. However, patients on antipsychotics are often excluded from unmodified lifestyle-intervention weight management programmes and trials.Objectives: To determine if weight loss is possible for antipsychotic-medicated obese patients when enrolled in an unmodified lifestyle-intervention weight man...

Introduction: Infertility affects 15% of couples worldwide. Male factors account for half of cases seeking medical care.Objectives and methods: To ascertain whether the American Association of Clinical Endocrinologists (AACE) guidelines regarding gonadotrophin induction of spermatogenesis in men with hypogonadism are being followed in our unit. Data were collected retrospectively from clinical records.Results: 26 couples were ident...

Introduction: Patients in secure forensic psychiatric units are at high risk of developing obesity due to complex interplay of factors including antipsychotic medications, restrictions on freedom and poor motivation to healthy lifestyle and physical activities.Aim: To establish the prevalence of obesity and metabolic syndrome (MetS) in a secure forensic psychiatric hospital in the Republic of Ireland (ROI).Methods: We carried out a...

Severe obesity continues to dramatically increase in prevalence and is associated with significant mortality and morbidity. The American Society of Metabolic and Bariatric Surgery recommends that bariatric surgery only be performed on those with severe obesity. Gastric bypass surgery decreases mortality by 40% at 7.5 years.Using photographs of volunteers from a hospital based weight management clinic, we performed a survey of endocrinologists, general pr...

A retrospective analysis of the results of all intra-arterial calcium stimulations performed at St. Vincent’s Hospital, Dublin, in the years 2001-2006. All patients with symptoms suggestive of hypoglycemia had 72 hour fasting test with evidence of inappropriately elevated insulin and c-peptide at the time of hypoglycemia. These patients were investigated further with pancreatic imaging and selective intra-arterial calcium stimulation with hepatic venous sampling (ASVS). A...

Introduction: Primary hypogonadism (PHG, testosterone <10.5 nmol/l and LH >9.5 U/l) without a recognisable cause affects ~2% of community-dwelling middle-aged and older men. We sought to identify the clinical significance of, and risk factors for, this apparently age-related hypogonadal state.Methods/design: The European Male Ageing Study (EMAS) is a prospective observational cohort survey of 3.369 community-dwelling men aged 40–79 in eight ...