Searchable abstracts of presentations at key conferences in endocrinology

ea0086p96 | Neuroendocrinology and Pituitary | SFEBES2022

A case of chronic hyponatremia secondary to SIADH treated with low dose Tolvaptan to prevent recurrent hospital admission and proven cost effective

Ahsan Masato , Smurthwaite Hannah , Mani Hamidreza

Introduction: Tolvaptan, a selective vasopressin 2 receptor antagonist is proving beneficial in managing hyponatremia secondary to SIADH.Case report: A 75-year-old male with history of traumatic SAH developed hyponatremia secondary to SIADH. He had multiple admissions with symptomatic hyponatremia. His sodium level kept dropping despite putting on fluid restriction and trial of sodium chloride tablets. He was started on Tolvaptan 7.5 once weekly initiall...

ea0086p141 | Thyroid | SFEBES2022

Are we following NICE guidelines in classifying hyperthyroid patients presenting to endocrinology clinic in a DGH?

Khalil Ghayyur , Ahsan Masato , Johnson Adam , Smurthwaite Hannah , Mani Hamidreza

Background: Nice guideline recommends using TSH receptor antibody as a tool for classification of hyperthyroid patients; and considering technetium scanning of the thyroid gland if TRAbs are negative. Early diagnosis of TED is also essential for treatment to be effective. The most common way to assess the severity of TED is to use the Clinical Activity Score (CAS) 7-point scale.Objectives: We aimed to evaluate if hyperthyroid patients are classified corr...

ea0094p102 | Neuroendocrinology and Pituitary | SFEBES2023

Macroprolactinoma management during pregnancy

Morrison Amy , Ahsan Masato , Bremner Emma , Todd Diane , Levy Miles

Case: This 23-year-old lady initially presented in 2013 with headaches, galactorrhoea and secondary amenorrhoea. Visual fields were normal to confrontation. Prolactin levels were elevated at 3028miu/l. MRI pituitary revealed a 14x13x15mm adenoma pushing the pituitary stalk posteriorly, and compressing the left side of the optic chiasm.Initial Management: Cabergoline was commenced (250mg twice weekly), with good clinical ...

ea0094p374 | Neuroendocrinology and Pituitary | SFEBES2023

A case of pituitary apoplexy on long term cabergoline for prolactinoma

Ahsan Masato , Mahbub Swapnil Asif , Zaman Sajnin , Macriyiannis Thrasos , Venugopalprabhu Vimal

Pituitary apoplexy is an uncommon, but well recognised clinical syndrome, which usually results from ischaemic or haemorrhagic necrosis of pituitary gland, which is frequently precipitated by an existing pituitary adenoma. Early diagnosis of this condition is essential as prompt management may be life and vision saving. We are highlighting a case of Pituitary apoplexy on long term Cabergoline for Prolactinoma.Case report: A 62 year old l...

ea0094p263 | Reproductive Endocrinology | SFEBES2023

A case of high testosterone in an asymptomatic female patient

Ahsan Masato , Zaman Sajnin , Saeed Mohamed , Gohil Shailesh , Reddy Narendra , Levy Miles

Introduction: Testosterone <5nmol/l is commonly seen in conditions such as PCOS however when testosterone is >5nmol/l, concerns start to rise about more sinister causes. Here, we present a case of a female who was referred to clinic with testosterone >5mmol/lCase: A 32 year old presented to the GP with a heavier than usual menstrual period. For an unknown reason, the GP checked testosterone, which came back a...

ea0099p595 | Late-Breaking | ECE2024

Comparison of hydrocortisone and prednisolone in managing adrenal insufficiency– HYPER-AID study interim results from a tertiary care centre

Ahsan Masato , Morrison Amy , Fowkes Natasha , Gohil Shailesh , J Levy Miles , Meeran Karim , Reddy Narendra

Background: Adrenal insufficiency (AI) requires life-long glucocorticoid substitution therapy (1), and bears significant risks of infection, cardiovascular (CV) & metabolic disease burden. Historically Hydrocortisone (HC) has been the mainstay of treatment. Prednisolone is a once-daily alternative due to a longer half-life (up to 3.2 hrs). Currently, there is no discernible evidence supporting the superiority of either medication (2).Objective: To ex...

ea0099ep1230 | Late Breaking | ECE2024

Audit on management of addison’s disease in pregnancy

Ahsan Masato , Bremner Emma , Todd Diane , Roy Chandrima , J Levy Miles , Gohil Shailesh , Reddy Narendra

Background: Primary adrenal insufficiency or AddisonÂ’s disease (AD) is characterized by glucocorticoid and mineralocorticoid deficiency due to lesion of the adrenal glands through different mechanisms (1). AddisonÂ’s disease is a risk factor for adverse maternal and neonatal outcomes. Close monitoring is required for these patients during the intrapartum and postpartum periods.(2)Objective: Retrospective evaluation of the management of Addison&#...

ea0077p47 | Metabolism, Obesity and Diabetes | SFEBES2021

Leicestershire wide steroid safety programme 2019-21 and effectiveness of electronic alert on prescription software in a tertiary centre

Ahsan Masato , Zaman Sajnin , Mifsud Roberta B , Reddy Narendra L , Bremner Emma , Barrowcliffe Mary , Bhake Ragini C , Levy Miles J

Background: Omission of steroids and unsafe steroid prescription in Adrenal insufficiency (AI) patients during intercurrent illness or surgery is unfortunately common, and can lead to adrenal crisis and potentially death. Anna Mitchell et al, New Castle-upon-Tyne have demonstrated potential use of electronic automation with steroid alerts to minimise human error for ensuring patient safety.Objectives: 1. Similar use of artificial intelligence wa...

ea0094p23 | Adrenal and Cardiovascular | SFEBES2023

A case of primary adrenal hydatid cyst

Ur Rehman Abaid , Ahsan Masato , Sule Zakary , Jones Max , Zaman Sajnin , Shafiq Shahriar , Morrison Amy , Levy Miles

Introduction: Hydatid disease (Cystic echinococcosis) is a zoonotic parasitic infection with the Echinococcus granulosus tapeworm resulting in cyst(s) within viscera. The predominant site for cyst formation is the live, with primary adrenal cyst accounting for less than 0.5% of presentation. We report a case of primary adrenal hydatid disease.Case report: A 62 year old female presented to the hospital with history of rig...

ea0077p15 | Adrenal and Cardiovascular | SFEBES2021

Giant bilateral adrenal mylelolipoma in a patient with congenital adrenal hyperplasia

Zaman Sajnin , Ahsan Masato , Lloyd David , Bharadwaj Neil , Bremner Emma , Barrowcliffe Mary , Bhake Ragini C , Kenchaiah Manohara , Gohil Shailesh , Levy Miles J , Reddy Narendra L

Introduction: Congenital adrenal hyperplasia (CAH) is an inherited autosomal recessive disorder characterized by insufficient production of cortisol and high androgens. Myelolipoma is a benign neoplasm of adrenal gland composing mature adipose tissue and scattered islands of hematopoietic elements. We report a case of rare association of giant bilateral adrenal mylelolipoma in a congenital adrenal hyperplasia patient who was non-compliant with medication.<p class="abstext"...