Endocrine Abstracts

Introduction: Dupuytren’s disease (DD) corresponds to a chronic palpable thickening of the palmar aponeurosis which leads to different degrees of irreducible flexion of the fingers. It is one of the manifestations of hand syndrome in diabetes mellitus. We highlight through this report the occurrence of DD as a manifestation of diabetic hand syndrome in a patient with type 2 diabetes mellitus.Observation: A sixty-six year old patient, truck driver, t...

Introduction: Human immunodeficiency virus (HIV) infection and certain antiretroviral (ARV) treatments are associated with an increased risk of developing certain chronic comorbidities including type 2 diabetes, which is more prevalent in HIV-infected individuals. The coexistence of diabetes and HIV infection makes the standard of care more complex. The objective of this work is to discuss the relationship between these two comorbidities and to update physicians on the diagnos...

Introduction: Polyuro-polydipsia syndrome (PPS) is defined by urine excretion rate more than 3L per day, associated with a parallel increase in oral fluid intake. It poses problems of positive and etiological diagnosis. We discuss in this observation the modalities of exploration of PPS and its main etiologies.Case report: A 60-year-old patient, diabetic for 10 years, controlled on metformin, admitted for PPS evolving for 37 years. Clinical examination w...

Introduction: Patients with PTC usually have excellent outcomes with appropriate therapy, while up to 30% of patients present with aggressive disease, including patients with locoregional recurrence and distant metastasis.The aim: Of this study is to analyze the characteristics of patients with papillary carcinoma of the thyroid with locoregional and distant recurrences.Résults: We included 12 cases of locoregional and distant...

Introduction: Wernicke’s encephalopathy is a rare neurological disorder initially described in alcohol-dependent and malnourished patients. It is characterised by confusion, ataxia and nystagmus. It is caused by thiamine deficiency. We report the case of a patient with hyperemesis gravidarum and hashitoxicosis complicated by Wernicke’s encephalopathy Observation: A 22 year old patient, 1G0P, without any particular pathological history, was admi...

Introduction: Parkinson’s disease (PD) is one of the most common neurodegenerative disorders characterized by bradykinesia, tremor, rigidity and postural instability as well as neurocognitive impairment and depression. Studies found a significant association between thyroid dysfunction and an increased risk of PD. We report the case of a patient treated for PD who had also Hashimoto’s thyroiditis, and we discuss the association of thyroid dysfunction with risk of PD....

Introduction: The non-Hodgkin lymphomas (NHL) involve extralymphatic sites more often than does Hodgkin lymphoma; consequently, tumor involvement of almost every abdominal organ has been recorded. Adrenal involvement in patients with NHL may be present at the time of initial assessment. however, adrenal insufficiency as a consequence of adrenal invasion is rare. We report a case of a patient diagnosed with NHL with breast and bilateral adrenal involvement.<p class="abstext...

Introduction: While hypercalcemia is extensively studied in cancer patients, the occurrence of hypocalcemia is not as commonly reported. The unique aspect of this case lies in severe hypocalcemia against the background of a malignant tumor of the cervix, a condition often associated with hypercalcemia.Case report: A 66-year-old patient, diabetic for 13 years with insulin therapy, is being treated for poorly differentiated squamous cell carcinoma of the c...

Introduction: Plasmapheresis is an extracorporeal blood purification method that removes potentially harmful macromolecules (molecular weight L15 - 50 kDa) from the blood. Pancreatitis is a potentially fatal complication of hypertriglyceridemia. The current mainstay of treatment for hypertriglyceridemia associated with pancreatitis includes heparin, insulin and lipid-lowering agents. Experience with plasmapheresis is limited. We report here our experience of using plasmapheres...

Introduction: MODY (maturity-onset diabetes of the young) is a group of heterogeneous diabetic disorders characterized by dysfunction of insulin secretion by the β-cell and genetically transmitted. MODY diabetes is thought to account for 2-5% of all diabetic disorders, but is often under-diagnosed. We report two suspected cases of MODY diabetes.Observations: Case 1: 40-year-old patient, known diabetic for 3 years, initially on Gliclazide 60 mg and M...