ea0086p119 | Reproductive Endocrinology | SFEBES2022
, Richardson Rachel
, Albert Anthony
, Hanyaloglu Aylin
, Jonas Kim
The Class A G protein-coupled receptor (GPCR), follicle-stimulating hormone receptor (FSHR), and its associated heterodimeric glycoprotein hormone (FSH) are essential for reproduction. As such, theyre key targets of assisted conception. Post-translational modification of FSH gives rise to two predominant glycosylation variants, which are modulated with ageing: partially glycosylated FSH (FSH21/18), predominates in womens reproductive prime (20s), displays fas...