Searchable abstracts of presentations at key conferences in endocrinology

ea0007p41 | Diabetes, metabolism and cardiovascular | BES2004

The N363S polymorphism of the glucocorticoid receptor in South Asians in the North East

Syed A , Irving J , Redfern C , Hall A , Unwin N , White M , Bhopal R , Alberti K , Weaver J

Some people with obesity have hormonal, metabolic and circulatory changes that constitute the metabolic syndrome that resemble characteristics of patients with Cushing's syndrome. A link between the two conditions, possibly genetic, has therefore been suspected, and the glucocorticoid receptor gene (GRL, 5q31-q32) has been one of the candidate genes.The single nucleotide polymorphism N363S is an ATT to GTT missense alteration within exon 2 of G...