Searchable abstracts of presentations at key conferences in endocrinology

ea0032p583 | Female reproduction | ECE2013

New endocrine and intracellular regulators of ovarian functions

V S Alexander

This is the review of original data concerning the role of some metabolic hormones (GH, leptin, ghrelin, obestatin), growth factors (IGF-I, IGFBPs, EGF, thrombopoietin), intracellular mediators of their action (cyclic nucleotides, protein kinases, PKA, MAPK, CDK, transcription factors, CREB, STAT-1, p53 and related cDNA, siRNA and miRNA gene constructs) on basic ovarian functions (cell proliferation, apoptosis, secretion, oogenesis, ovulation, production and viability of pups)...

ea0024oc1.3 | Oral Communications 1 | BSPED2010

Semen cryopreservation in adolescent minors with cancer: a 10-year experience

Gan H W , Davar Z , Alexander S , Gomes S , Davies M , Salim R , Spoudeas H A

Background: Increased childhood cancer survival has resulted in an accruing adult cohort faced with potential infertility. Pre-treatment semen cryopreservation can protect reproductive capacity in adolescent minors, but continued unique legal, ethical and educational barriers prevent consistent service provision across the UK. The effect of pubertal maturation, disease and treatment on the ability to produce sperm also remains poorly defined in this cohort. We present our 10-y...