Endocrine Abstracts

Introduction: Thyroid hormones (TH) are essential regulators of metabolism and increase energy expenditure (EE). Mitochondria-rich brown adipose tissue (BAT) is specialised in thermogenesis and significantly contributes to EE. BAT contains essential components of TH action but TH transporters like MCT8 have not been characterised so far. As direct effects on O2 consumption and mitochondrial action have not been investigated before we tested MCT8 expression and direct effects o...