Searchable abstracts of presentations at key conferences in endocrinology

ea0032p207 | Cardiovascular Endocrinology & Lipid Metabolism | ECE2013

Subclinical atherosclerosis and cardiovascular risk in healthy, young menopausal women

Armeni Eleni , Stamatelopoulos Kimon , Georgiopoulos Georgios , Kouskouni Evangelia , Creatsa Maria , Alexandrou Andreas , Papamichael Christos , Lambrinoudaki Irene

Introduction: Delayed diagnosis of a cardiovascular event is related with higher case-fatality rate in women as compared to men. In fact, accumulating evidence supports an association between the menopausal status and the development of cardiovascular disease (CVD). We aimed to assess the extent of subclinical vascular disorders in young, healthy postmenopausal women, with respect to the calculated cardiovascular risk.Methods: This cross-sectional study ...

ea0022p150 | Cardiovascular endocrinology and lipid metabolism | ECE2010

Genetic polymorphisms associated with cardiovascular risk correlate with dyslipidaemia in healthy postmenopausal women

Papadimitriou Dimitra , Kaparos George , Rizos Dimitrios , Armeni Eleni , Creatsa Maria , Alexandrou Andreas , Christodoulakos George , Lambrinoudaki Irene

Objective: To assess the impact of genetic polymorphisms associated with increased cardiovascular risk on the lipid profile in healthy postmenopausal women.Methods: The study population consisted of 84 women between 49–69 years who had been menopausal for at least one year. The genetic polymorphisms examined were the following: Glycoprotein IIIa leu33pro, Apolipoprotein E2/E3/E4, Methylenotetrahydrofolate reductase ala222val, Apolipoprotein B arg350...

ea0022p738 | Steroid metabolism & action | ECE2010

Androgenicity is enhanced in the presence of ala222val polymorphism in healthy postmenopausal women

Papadimitriou Dimitra , Kaparos George , Rizos Dimitrios , Armeni Eleni , Kreatsa Maria , Alexandrou Andreas , Christodoulakos George , Lambrinoudaki Irene

Objective: To assess the interrelation of the MTHFR ala222val polymorphism, correlated with increased rates of cardiovascular disease, with indices of androgenicity in healthy postmenopausal women.Methods: The population of this cross-sectional study consisted of 84 healthy women who had been menopausal for at least one year. The examined polymorphism was Methylenetetrahydrofolate reductase ala222val, while the hormonal assays included Testosterone, Sex ...

ea0070aep1090 | Hot topics (including COVID-19) | ECE2020

Climacteric symptoms and stress management techniques in peri- and early postmenopausal women

Armeni Eleni , Augoulea Areti , Palaiologou Anastasia , Christidi Foteini , Soureti Anastasia , Alexandrou Andreas , Panoulis Konstantinos , Chroussos Georgios , Zervas Ioannis , Lambrinoudaki Irene

Introduction: The hypothalamic-pituitary-ovarian and/or adrenal axis as well as the autonomous nervous system affect significantly the intensity of menopausal symptoms Pre-existing levels of stress may affect the individual perception of menopausal symptoms. We aimed to evaluate the efficacy of a structured stress management program to reduce levels of stress and severity of climacteric symptoms, in a sample of middle-aged Greek women.Methods: The sample...

ea0022p461 | Female reproduction | ECE2010

Estrogen plus progestin treatment: effect of different progestin components on serum markers of apoptosis in healthy postmenopausal women

Karaflou Maria , Kaparos George , Rizos Demetrios , Logothetis Emanuel , Alexandrou Andreas , Aravantinos Leon , Creatsa Maria , Christodoulakos George , Lambrinoudaki Irene , Kouskouni Evangelia

Objective: To investigate the effect of two hormone therapy (HT) regimens differing only in their progestin component on serum markers of apoptosis.Design: Randomized, double-blinded study.Patients: One hundred healthy postmenopausal women.Interventions: Patients were randomized to 17β-estradiol 1 mg/drosperinone 2 mg (E2/DSP) or 17β-estradiol 1 mg/norethisterone acetate 0.5 mg (E2</...

ea0022p462 | Female reproduction | ECE2010

The effect of hormone therapy and tibolone on serum CD40L and ADAM-8 in healthy postmenopausal women

Lambrinoudaki Irene , Karaflou Maria , Kaparos George , Grigoriou Odysseas , Alexandrou Andreas , Panoulis Constantinos , Logothetis Emanuel , Creatsa Maria , Christodoulakos George , Kouskouni Evangelia

Background/aim: The role of neutrophils and platelets in atherothrombotic disease is well established. The aim of our study was to investigate the effect of hormone therapy and tibolone on the soluble markers of neutrophil and platelet activation, ADAM-8 and CD40L respectively, in healthy postmenopausal women.Subjects and methods: One hundred and six healthy postmenopausal women were randomly allocated to: estradiol plus drospirenone (E2/DSP),...

ea0070aep296 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Pulse wave velocity and circulating Retinol binding protein 4: A cross sectional association in early postmenopausal women

Armeni Eleni , Nigdelis Meletios P , Chondrou Asimina , Anagnostis Panagiotis , Augoulea Areti , Rizos Dimitrios , Kaparos George , Alexandrou Andreas , Goulis Dimitrios G , Patras Raphael , Aivalioti Evmorfia , Stamatelopoulos Kimon , Lambrinoudaki Irene

Introduction: Recent evidence recognized the value of Retinol-Binding Protein (RBP4), as potential biomarker of cardiovascular and cerebrovascular pathology. The possible association between RBP4 and functional vascular disease remains unexplored, while recent data in postmenopausal populations suggested lack of association between RBP4 and subclinical atherosclerosis. We evaluated the possible link between RBP4 and menopause-specific cardiovascular risk factors, in a sample o...

ea0070aep1003 | Hot topics (including COVID-19) | ECE2020

The NOS3 and CYBA gene polymorphisms are associated with subclinical atherosclerosis and arterial stiffness in premenopausal women

Armeni Eleni , Chatzivasileiou Panagiota , Stergiotis Stefanos , Rizos Demetrios , Kaparos Georgios , Augoulea Areti , Alexandrou Andreas , Georgiopoulos Georgios , Laina Aggeliki , Stamatelopoulos Kimon , Lambrinoudaki Irene

Introduction: Differences in the prevalence and prognosis of cardiovascular disease have been linked with gender specific risk factors as well as the differential impact of sex hormones. Moreover, specific genetic polymorphisms may increase further the risk of cardiovascular disease development. Polymorphisms of genes encoding the NADPH/NADPH oxidase system and the endothelial nitric oxide synthase (eNOS) have been associated with atherosclerosis in the general population, but...

ea0070aep1012 | Hot topics (including COVID-19) | ECE2020

Subclinical atherosclerosis is associated with anti-mullerian hormone levels in reproductively women

Armeni Eleni , Stergiotis Stefanos , Chatzivasileiou Panagiota , Augoulea Areti , Anagnostis Panagiotis , Rizos Demetrios , Kaparos George , Alexandrou Andreas , Georgiopoulos Georgios , Kontogiannis Christos , Stamatelopoulos Kimon , Lambrinoudaki Irene

Introduction: The prevalence of cardiovascular disease in reproductively active women has received limited attention. Recent data indicated possible adverse effect of non-typical obstetrical risk factors with regards to cardiovascular function. We aimed to evaluate the potential association between anti-mullerian hormone (AMH), a known marker of ovarian reserve, with subclinical atherosclerosis in young premenopausal women.Methods: This was a cross-secti...

ea0032p187 | Cardiovascular Endocrinology &amp; Lipid Metabolism | ECE2013

TSH and arterial stiffness in healthy postmenopausal women

Armeni Eleni , Stamatelopoulos Kimon , Rizos Demetrios , Georgiopoulos Georgios , Kazani Maria , Alexandrou Andreas , Deligeoroglou Efthymios , Livada Alexandra , Psychas Charalampos , Creatsa Maria , Bouboulis George , Alevizaki Maria , Lambrinoudaki Irene

Introduction: Thyroid dysfunction, whether overt or subclinical, has a significant effect on the cardiovascular system. On the other hand, fluctuation of thyroid hormones within the normal range has been associated with long-term health risks, and might have an impact on the vasculature. This study assessed the effect of thyroid hormones on surrogate markers of arterial structure and function in a sample of euthyroid postmenopausal women.Methods: This cr...