Searchable abstracts of presentations at key conferences in endocrinology

ea0035p860 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Evolution of glucose tolerance status after treatment of acromegaly: a prospective study in 57 patients

Jonas Corinne , Alexopoulou Orsalia , Maiter Dominique

Background: Acromegaly is frequently associated with impaired glucose tolerance (IGT) or diabetes and treatment has also differential effects on glucose metabolism depending on specific type of medication.Objective: To study in 57 acromegalic patients evolution of glucose metabolism according to disease activity and treatment.Methods: IGF1 measurement, oral glucose tolerance test (OGTT) and HOMA test to evaluate insulin sensitivity...

ea0090p391 | Endocrine-related Cancer | ECE2023

Urinary free cortisol is an independent predictive factor for early distinction between ectopic ACTH secretion and pituitary Cushing’s disease

Raluca Furnica , Collard Alix , Frank Cornelis , Alexopoulou Orsalia , Maiter Dominique

Introduction: The poor prognosis of patients with Cushing’s syndrome due to ectopic ACTH secretion (ECS) requires prompt diagnosis and management of the disease. Objectives: To find clinical and biological differences between ECS and pituitary Cushing’s disease (CD) at diagnosis and to determine whether any of them may be a potential predictor for early suspicion of ECS. Methods: This was a retrospective case-nested study...

ea0022p781 | Thyroid | ECE2010

Coagulation disorders in hypothyroidism: effects of thyroid hormones deficiency and/or of TSH?

Yango John , Alexopoulou Orsalia , Eeckoudt Stephane , Hermans Cedric , Daumerie Chantal

Various haemostatic abnormalities have been associated with thyroid dysfunction, especially with hypothyroidism. The underlying mechanisms are not well established.The aim of the study was to evaluate the primary and secondary haemostasis in patients with severe hypothyroidism, to assess the role of thyroid hormone deficiency and to determine whether increased serum TSH level despite normal free thyroid hormone concentrations could influence the coagulat...

ea0084ps2-07-66 | Graves’ Disease 1 | ETA2022

Influence of thyroperoxydase and thyroglobulin antibodies on the presentation and the evolution of medically treated graves’ disease

Matei Constantinescu Stefan , Hospel Julien , Daumerie Chantal , Alexopoulou Orsalia , Maiter Dominique , Burlacu Maria-Cristina

Introduction: Thyrotropin receptor stimulating antibodies (TRAb) are responsible for Graves’ disease (GD) manifestations. Other thyroid antibodies, namely thyroperoxidase (TPOAb) and thyroglobulin (TGAb) antibodies are highly prevalent in GD, but their roles in GD presentation and evolution are controversial.Methods: We retrospectively analysed TPOAb and TGAb levels and evolution in 88 consecutive patients with newly diagnosed GD between 2000 and 20...

ea0090p688 | Pituitary and Neuroendocrinology | ECE2023

Incidental pituitary macroadenoma: natural history and surgical results

Matei Constantinescu Stefan , Alexopoulou Orsalia , Duprez Thierry , Furnica Raluca , Fomekong Edward , Raftopoulos Christian , Maiter Dominique

Introduction: The Incidental diagnosis of non-functioning pituitary macroadenomas (NPFMA) is becoming more prevalent with the spread of modern imaging techniques. More clinical data about their natural history and surgical results are needed. Methods: We retrospectively analyzed medical files of patients referred to our clinic for an incidental NFPMA between 2010 and 2019. In particular, we compared patients that experienced tumor growth or not during su...