Searchable abstracts of presentations at key conferences in endocrinology

ea0038p228 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2015

Characterising fat distribution and response to weight loss in idiopathic intracranial hypertension

Ali Fizzah , O'Reilly Michael , Botfield Hannah , Markey Keira , Tomlinson Jeremy , Arlt Wiebke , Sinclair Alexandra

Introduction: Idiopathic intracranial hypertension (IIH) occurs in young obese women (>90%) but little is known about the metabolic characteristics in these patients. We aimed to characterise IIH fat distribution, metabolic phenotype and evaluate alterations following weight loss.Methods: IIH and matched (BMI/sex) healthy obese controls were recruited. Metabolic indices (fasting lipid, glucose, insulin), anthropological measures and body composition ...

ea0038p193 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2015

Women with idiopathic intracranial hypertension have a distinct andro-metabolic signature compared to polycystic ovary syndrome and simple obesity

O'Reilly Michael , Kempegowda Punith , Botfield Hannah , Ali Fizzah , Taylor Angela , Hughes Beverley , Tomlinson Jeremy , Arlt Wiebke , Sinclair Alex

Context: Idiopathic intracranial hypertension (IIH) is characterised by elevated intracranial pressure and occurs predominantly in obese premenopausal women. Signs and symptoms of polycystic ovary syndrome (PCOS) often coexist in IIH. Here we compared the androgenic and metabolic phenotypes in IIH, PCOS and simple obesity.Patients and methods: We studied 25 patients with IIH (mean age 34.4±9.2 years; mean BMI 37.8±5.2 kg/m2), in comp...