Searchable abstracts of presentations at key conferences in endocrinology

ea0034p354 | Steroids | SFEBES2014

Dexamethasone-related adrenal insufficiency in patients with solid brain tumours

Currie Helen , Ali Muzzammil

Dexamethasone is used to reduce cerebral oedema thus relieve symptoms of raised intracranial pressure. Long-term use causes suppression of the hypothalamic–pituitary–adrenal axis, which can lead to adrenal insufficiency. Undiagnosed, significant morbidity and mortality can occur from Addisonian crisis. The aim of this audit was to discover the relationship between adrenal insufficiency and long-term steroid use, in order to make recommendations for the use and withdr...

ea0039ep95 | Other | BSPED2015

Effect of dietetic management on weight in children with Bardet-Biedl syndrome

Uday Suma , Ali Muzzammil , Azam Waseema , Barrett Timothy

Introduction: Bardet-Biedl syndrome (BBS) is a monogenic disease characterized by retinitis pigmentosa (>90%), obesity (72–86%), insulin resistant diabetes, and hypogonadism. Weight management is challenging due to frequent association of learning and visual impairment. At our BBS MDT clinic, dietetic review is provided at each visit. Dietetic input focuses primarily on reduced fat and sugar content in diet and exercise is encouraged. Individualised written dietary pl...

ea0039ep104 | Pituitary and growth | BSPED2015

Overcoming the need for a second test: an evaluation of anthropometric, biochemical, and radiological parameters in the diagnosis of GH deficiency

Ali Muzzammil , Casey Angela , Kirk Jeremy , Dias Renuka

Background: The investigation of short stature includes evaluation of a number of clinical, radiological, and biochemical factors. This often includes dynamic function testing to rule out abnormalities of the hypothalamic–pituitary axis to rule out GH deficiency (GHD). NICE guidance advises that two GH stimulation tests demonstrating subnormal GH peak <6.7 μg/ml (20 mU/l) is required to confirm the diagnosis of GHD.Objectives: To interrogat...