Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep1290 | Clinical Cases–Thyroid/Other | ECE2015

Nephrogenic syndrome of inappropriate antidiuresis secondary to an activating mutation in the arginine vasopressin receptor AVPR2

Powlson Andrew S , Challis Benjamin G , Lagnado Alice , Halsall David J , Semple Robert K , Gurnell Mark

Case history: A 38-year-old man was referred with a 12-month history of recurrent bouts of transient hyponatraemia (serum sodium ranging from 115 to 125 mmol/l). Citalopram, which he was taking for depression, was discontinued, but the episodes continued.Initial investigations: Whilst symptomatic, and clinically euvolaemic, his biochemical profile was consistent with a syndrome of inappropriate antidiuresis (SIAD): sodium 124 mmol/l, potassium 4.5 mmol/l...