Searchable abstracts of presentations at key conferences in endocrinology

ea0044p232 | Reproduction | SFEBES2016

Levels of reactive oxygen species (ROS) in the seminal plasma predicts the effectiveness of L-carnitine to improve sperm function in men with infertility

Vessey Wayne , McDonald Cassandra , Virmani Ashraf , Almeida P. , Jayasena Channa , Ramsay Jonathan

Background: Oxidative stress is implicated in the pathogenesis of primary male infertility. Some studies suggest that administration of the amino acid derivative anti-oxidant, L-carnitine, may improve sperm quality. No previous study has investigated whether the anti-oxidant effects of L-carnitine relate to changes in sperm quality in men with infertility.Aim: Investigate whether L-carnetine significantly improves sperm function, and whether baseline lev...

ea0090p708 | Pituitary and Neuroendocrinology | ECE2023

Congenital, isolated, and lifetime growth hormone deficiency provides superior cognitive performance in senescence

Batista Vanderlan O. , Kellner Michael , Salvatori Roberto , Oliveira Walter , Faro Andre , Santos Lucas B. , Melo Enaldo V. , Oliveira-Santos Alecia A. , Oliveira Carla R. P. , Almeida Viviane , Barros-Oliveira Cynthia S. , Santos Elenilde G. , Santana Nathalie O. , Villar-Gouy Keila R. , Leal Angela , Amorim Rivia S. , H. Aguiar-Oliveira Manuel

Mice with isolated GH deficiency (IGHD) due to GHRH receptor mutations live longer than their normal siblings with an extended healthspan, i.e., the period of life free from disabilities. Human IGHD individuals due to a mutation in the GHRH receptor gene from Itabaianinha, Brazil, has a normal lifespan with an extended healthspan (1). Our hypothesis is that their aging is accompanied by a delayed cognitive decline. Accordingly, we used the Literacy Independent Cognitive Assess...