Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep460 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

New-onset diabetes after transplantation (NODAT): an evaluation of risk factors in renal transplantation

Almeida Raquel , Campos Andreia , Martins La Salete , Dores Jorge

Background: The identification of patients with high risk of diabetes mellitus (DM) after renal transplantation in the pre-transplantation period is crucial for the prevention of this pathology and reduction of the risk of cardiovascular morbidity and mortality. With this study we intended to identify the risk factors for NODAT in renal transplantation.Methods: All patients submitted to renal transplantation at Centro Hospitalar do Porto between 01/01/20...

ea0049ep462 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

New onset diabetes after transplantation (NODAT): frequency and characterization of patients in renal transplantation

Almeida Raquel , Campos Andreia , Martins La Salete , Dores Jorge

Background: The identification of patients with NODAT in renal transplantation is essential to establish adequate treatment and to reduce cardiovascular risk and graft failure. With this study we intended to evaluate the frequency of NODAT and to characterize patients with NODAT in renal transplantation.Methods: All patients submitted to renal transplantation at Centro Hospitalar do Porto between 01/01/2009 and 12/31/2013 were retrospectively evaluated. ...

ea0037ep173 | Reproduction, endocrine disruptors and signalling | ECE2015

Persistent Mullerian duct syndrome: a case report

Almeida Raquel , Canha Antonio , Santos Jorge , Rocha Anabela , Dores Jorge

Persistent Mullerian duct syndrome (PMDS) is a rare disorder of sex development characterized by the persistence of Mullerian duct derivatives in a genotypic (46,XY) and phenotypic normally virilised male. PMDS is transmitted in an autosomal recessive manner, caused by mutations in the anti-Mullerian hormone gene or in the gene encoding the AMH receptor. The authors report a case of a male patient aged 62 years, with bipolar disorder, referred to the endocrinologist by inciden...

ea0049ep350 | Endocrine tumours and neoplasia | ECE2017

A suspicious case of multiple endocrine neoplasia

Pereira Teresa Alves , Furtado Ines , Amado Ana , Ferreira Lia , Almeida Raquel , Palma Isabel

Introduction: Multiple endocrine neoplasia (MEN) syndromes are rare entities characterized by the occurrence of tumors involving two or more endocrine glands in a single patient. These syndromes are classified as type 1 or 2 according to specific phenotypic characteristics. MEN2 encompasses three different subtypes: MEN2A, MEN2B and familial medullary thyroid carcinoma. More recently a syndrome related to mutations in the CDKN1B gene has been described – the syndrome of m...

ea0040p15 | (1) | ESEBEC2016

Post-pancreatectomy persistent adult nesidioblastosis: follow-up of 24 years

Almeida Raquel , Santos Ana Paula , Gomes Jose Teixeira , Lima Bastos , Bacelar Conceicao

Introduction: Adult nesidioblastosis is a rare entity that has motivated the publication of several case reports, but long-term outcomes are rarely described. Distal or sub-total pancreatectomy is indicated in cases of severe symptoms or lack of response to medical treatment. We report the case of a patient with persistent nesidioblastosis after pancreatectomy keeping under medical treatment for 24 years.Clinical case: Woman currently with 81-years old, ...

ea0037ep460 | Diabetes (complications & therapy) | ECE2015

Establishing the relationship between third-trimester foetal abdominal circumference, birthweight, and neonatal morbidity in gestational diabetes

Pereira Maria Teresa , Garrido Susana , Almeida Raquel , Vilaverde Joana , Pichel Fernando , Pinto Clara , Goncalves Joaquim , Dores Jorge

Introduction: Gestational diabetes (GD) is associated with a significantly higher risk of perinatal complications. It has been suggested that third-trimester (3thT) foetal abdominal circumference (fAC) determination is an important predictor of macrossomia and large for gestational age (LGA).Aims: The purpose of this study was to evaluate the association between the 3thT fAC percentile with birthweight (BW) and adverse neonatal outc...

ea0037ep552 | Obesity and cardiovascular endocrinology | ECE2015

Influence of normal food intake on the lipid profile of diabetic patients

Garrido Susana , Almeida Raquel , Pereira Teresa , Ferreira Lia , Neto Helena , Vilaverde Joana , Pichel Fernando , Oliveira Jose Carlos , Palma Isabel

Introduction: The need to fast for the determination of lipid profile has been discussed in the past years, for several reasons – i) most of the day time is spent in a postprandial state; ii) the lipid concentrations seem to be only slightly affected by a normal meal; both fasting and postprandial can predict cardiovascular risk.Aim: Determine the influence of normal food intake on the lipid profile of diabetic patients.Method...

ea0056ep15 | Adrenal and Neuroendocrine Tumours | ECE2018

IGF-2-oma: a diagnosis to be considered in a patient with a leiomyosarcoma and recurrent hypoglycemia

Fonseca Liliana , Ferreira Lia , Pereira Teresa Alves , Lopes Ana , Almeida Raquel , Vilaverde Joana , Pereira Maria Teresa , Cardoso Helena

Introduction: Non-islet cell tumor induced hypoglycemia (NICTH) is a paraneoplastic phenomenon involving many types of tumors. It is associated with the secretion of incompletely processed precursors of IGF-2 resulting in a persistent insulin-like activity and hypoglycemia. Most commonly, IGF-2–linked hypoglycemia has been observed in patients with solid mesenchymal or epithelial tumors. Typically, elevated IGF-2 levels are associated with suppressed plasma levels of insu...

ea0049ep496 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Maturity onset diabetes of the young - clinical characteristics of a portuguese cohort

Amado Ana , Almeida Raquel , Carvalho Andre , Amaral Claudia , Freitas Claudia , Bacelar Conceicao , Vilaverde Joana , Cardoso Maria Helena , Teixeira Sofia , Borges Fatima

Introduction: Maturity onset diabetes of the young (MODY) accounts for 1-2% of all forms of diabetes mellitus (DM). As classic criteria that lead to its suspicion have low sensitivity, patients are often misdiagnosed with type 1 or type 2 DM. Correct classification of this type of diabetes becomes essential for proper management of the disease. Our objective was to describe clinical features of patients with MODY diagnosed at our institution.Methods: We ...

ea0041ep31 | Adrenal cortex (to include Cushing's) | ECE2016

Primary aldosteronism – results from the first Portuguese multicentre study

Nunes da Silva Tiago , Fernandes Vera , Martins Diana , Goncalves Diana , Almeida Raquel , Margarida Monteiro Ana , Neves Carolina , Simoes Helder , Marques Pedro , Alves Filipa , Pereira Maria

Primary Aldosteronism (PA) is the most prevalent cause of secondary hypertension. The aim of this work was to characterize the diagnostic workup, treatment and follow-up of confirmed PA.The adrenal tumour study group of the Portuguese Society of Endocrinology undertook the first retrospective multicentre study of Portuguese PA patients. Data was gathered from nine Portuguese Endocrinology centres (three in the north, one in the centre and five in the sou...