Searchable abstracts of presentations at key conferences in endocrinology

ea0014p211 | (1) | ECE2007

The metabolic changes induced by glucocorticoids: involvement of AMP-activated protein kinase

Christ-Crain Mirjam , Kola Blerina , Lolli Francesca , Fekete Csaba , Seboek Dalma , Wittman Gabor , Ajodha Sharon , Harvey-White Judith , Kunos George , Mueller Beat , Amaldi Giorgio , Giacchetti Gilberta , Boscaro Marco , Grossman Ashley , Korbonits Marta

Background: Excess glucocorticoids result in CushingÂ’s syndrome (CS) which is characterised by increased food intake, central obesity, dyslipidaemia and insulin resistance, leading to the metabolic syndrome. AMPK is a regulator of energy homeostasis and plays an important role in the regulation of appetite, glucose uptake, lipogenesis and gluconeogenesis. We hypothesised that the effects of corticosteroids on metabolism would be mediated by changes in AMPK activity in a t...

ea0013p166 | Diabetes, metabolism and cardiovascular | SFEBES2007

The effects of glucocorticoids on the expression of gluconeogenic and lipogenic enzymes in a rodent model of Cushing’s Syndrome

Christ-Crain Mirjam , Kola Blerina , Lolli Francesca , Fekete Csaba , Seboek Dalma , Wittman Gabor , Ajodha Sharon , Harvey-White Judith , Kunos George , Mueller Beat , Amaldi Giorgio , Giacchetti Gilberta , Boscaro Marco , Grossman Ashley , Korbonits Marta

This abstract was printed as a duplication of abstract P291 and corrected onlineBackground: Excess glucocorticoids result in CushingÂ’s syndrome (CS) which is characterised by increased food intake, central obesity, dyslipidaemia and insulin resistance, leading to the metabolic syndrome. AMPK is a regulator of energy homeostasis and plays an important role in the regulation of appetite, glucose uptake, lipogenesis and gluconeogenesis. We hypothesised...