Searchable abstracts of presentations at key conferences in endocrinology

ea0081p185 | Reproductive and Developmental Endocrinology | ECE2022

Management of 46, XY 17 alpha-hydroxylase deficiency: a case report

Bouca Bruno , Cascao Mariana , Fiuza Pedro , Amaral Sara , Bogalho Paula , Silva-Nunes Jose

Introduction: 17 alpha-hydroxylase deficiency (17OHD) is a rare autosomal recessive disease caused by mutations in the CYP17A gene, representing 1% of cases of Congenital Adrenal Hyperplasia (CAH). The accumulation of mineralocorticoids and the glucocorticoid effect of corticosterone induce high blood pressure (HBP) and hypokalemia.Clinical Case: A 44 year-old female reporting HBP since the age of 20 years and without chronic medication, presented at the...

ea0081p496 | Thyroid | ECE2022

Outcomes of low-risk differentiated thyroid cancer submitted to radioactive iodine ablation - a comparative analysis in a single tertiary centre

Ivo Catarina , Amaral Sara , Raposo Nuno , Maciel Joana , Simoes Pereira Joana , Vilar Helena , Leite Valeriano

Introduction: The update of 2015 American Thyroid Association (ATA) guidelines recommend that radioactive iodine (RAI) ablation therapy should be used in line with patients’ risk stratification. However, there is no consensus on benefits of post-operative RAI ablation in patients with low risk differentiated thyroid cancer (DTC). The aim of this study is to compare the outcomes of patients with low risk DCT submitted to RAI ablation with those who were not.<p class="a...

ea0081p497 | Thyroid | ECE2022

Impact of 2015 ATA guidelines in 131I prescription in low-risk DTC

Amaral Sara , Ivo Catarina , Cordeiro Raposo Nuno , Maciel Joana , Simoes-Pereira Joana , Vilar Helena , Leite Valeriano

Background: To minimize potential harm from overtreatment of low-risk thyroid cancers, the 2015 American Thyroid Association (ATA) Guidelines recommend that radioactive iodine (RAI) ablation should not be routinely used in low-risk differentiated thyroid carcinoma (DTC). The present study aims to evaluate trends in RAI therapy in a tertiary center after the update of these Guidelines.Methods: Data from patients followed in a tertiary center with low-risk...

ea0081p760 | Thyroid | ECE2022

Added value for Graves’ orbitopathy management in a tertiary center – report of four cases

Manique Ines , Amaral Sara , Cortez Luisa , Palha Ana , Duarte Ana , Silva-Nunes Jose

Introduction: Graves orbitopathy is the major extrathyroidal manifestation of Graves Disease (GD). The approach depends on its clinical activity and severity. Treatment and referral to specialized centers, with Endocrinology and Ophthalmology, has a strong impact on the prognosis of Graves’ Disease (GD) and GO.Cases report: We report four cases of DG with OG. Their characteristics and clinical evolution are shown in Table 1.<table boarder="1" ce...

ea0073pep2.1 | Presented ePosters 2: Diabetes, Obesity, Metabolism and Nutrition | ECE2021

MODY 5: a rare cause of diabetes and chronic kidney disease – a report of 10 cases

Amaral Sara , Cláudia Martins Ana , Palha Ana , Bogalho Paula , Agapito Ana , Silva-Nunes Jose

IntroductionMaturity Onset Diabetes of the Young (MODY) affects 1–2% of diabetic patients. Subtype 5 (HNF1β mutation) is rare (~1% of all MODY subtypes) and extra-pancreatic manifestations are often present (chronic kidney disease (CKD), liver disease and/or genitourinary malformations).AimTo report and review confirmed MODY 5 cases in an Endocrinology Department.Meth...

ea0073aep115 | Calcium and Bone | ECE2021

Transient hypocalcaemia and definitive hypoparathyroidism after total thyroidectomy in Graves’ disease

Bruno Bouça , Amaral Sara , Vasques Miguel , Monteiro Nuno , Crespo Ana , José Coutinho , Tavares Paula , Bogalho Paula , José Silva-Nunes

IntroductionHypocalcaemia is a complication of total thyroidectomy (TT) and may be more frequent in patients with Graves’ disease. The reason for this increased risk is unclear and its occurrence has been associated with: ophthalmopathy severity, preoperative calcaemia and reimplantation of parathyroid glands.ObjectivesTo evaluate the risk factors for transient hypocalcaemia (TH) and definitive hypoparat...

ea0070aep174 | Bone and Calcium | ECE2020

Colour doppler ultrasound: Preoperative location of parathyroid adenomas in primary hyperparathyroidism

Amaral Sara , Rego Teresa , Vasques Miguel , Gutu Olga , Cláudia Martins Ana , Palha Ana , Sabino Teresa , Cortez Luísa , Afonso António , Fonseca Fernando , Carrilho Nuno , Mário Coutinho José , Tavares Paula , Agapito Ana

Introduction: Parathyroid adenoma is the most frequent cause of primary hyperparathyroidism (PHPT). In recent years minimally invasive surgical techniques have challenged the traditional bilateral neck exploration. There are different imaging techniques for preoperative location of parathyroid adenomas. In this study the authors review the role of Doppler ultrasound focusing on its safety, availability and affordability.Aim: To evaluate the role of Doppl...

ea0073aep246 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Risk factors associated with diabetic foot amputation among patients hospitalized for diabetic foot ulcer in a public hospital

Gutu Olga , Vasques Miguel , Inês Manique , Amaral Sara , Bruno Bouça , Prokop Joanna , Ana Cláudia Martins , António Afonso , José Neves , Silva-Nunes Jose

IntroductionDiabetic foot is one of the most devastating of chronic complications of diabetes mellitus (DM) and is responsible for about 25% of hospitalizations. Worldwide, the diabetic foot represents the main cause of non-traumatic lower limb amputation.Aim of the studyIdentification of risk factors for foot amputation among in patients hospitalized for diabetic foot in a tertiary public hospital in Portuga...