Endocrine Abstracts

Introduction: Testicular regression syndrome is defined as partial or complete absence of testicular tissue in the presence of a normal 46,XY male karyotype. This syndrome is very rare with an estimated prevalence of 1 case/20.000 males. Here we decribe a case of a testicular regression syndrome in an 18 years old patient. Case Report : We report the case of an 18 years old male patient followed for testicular regression syndrome since the age of 2, whic...

Introduction: Craniopharyngioma is a benign, slow-growing epithelial tumor of embryonic origin, originating in the pituitary stem or pituitary gland and developing in the sellar and/or suprasellar region. It is characterized by its considerable potential for extension, its tendency to recur, and its adhesions to surrounding structures.Case report: We report the case of a 60-year-old female patient with secondary amenorrhea at the age of 38 years, neglect...

Introduction: Thyroid abscess is a rare pathology, with the incidence of less than 1% of all thyroid diseases. We describe a unique case of thyroid abscess complicating post-covid-19 thyroiditis, which is the first case reported in Morocco to our knowledge.Case presentation: A 39-year-old man who had recently recovered from a mild episode of COVID-19 infection, consulted for weight loss, palpitations and neck pain. Examination of the neck revealed enlarg...

Introduction: Stiff-Person Syndrome (SPS) is a rare autoimmune neurological disorder that can be associated with other autoimmune diseases including type 1 diabetes mellitus (T1DM). The presence of alternative forms of autoimmune diabetes, such as latent autoimmune diabetes in adults (LADA) in SPS, is not well described.Case Report: A 63 years old male patient, his medical and family histories were non-specific. He developed progressive rigidity in trunc...

Introduction: Pituitary stalk interruption syndrome (PSIS) is a distinct developmental defect characterized by a thin or absent pituitary stalk, hypoplasia of the adenohypophysis, and ectopic location of the neurohypophysis.Case report: A 36 years old male patient, full term born by vaginal delivery, with birth asphyxia. Birth weight was 2800 g, length was 51 cm, and no other postnatal events were noticed. Psychomotor milestones were achieved normally. h...

Introduction: Klinefelter syndrome is a sex chromosomal aneuploidy caused by an addition of X chromosome in males (47,XXY). 48,XXXY is a rare variant of this syndrome which is characterised by the presence of two additional X chromosomes in males and is estimated to occur in 1/50 000 male births. Here we describe a rare case of a 48, XXXY Klinefelter’s variant in a 17 years old patient revealed by an intellectuel development delay. Case Report : The...

Introduction: Graves’ disease (GD) is a common autoimmune thyroid disease. The association between GD and thyroid carcinoma (TC) remains controversial. We describe two patients presenting this association.Case report: Case 1 a 46 years old woman with clinical history of type 2 diabetes, she was diagnosed with Graves’ disease and multiple nodules were found in her enlarged thyroid gland by ultrasonography. The patient underwent total thyroidecto...

Theassociation of primary hyperparathyroidism with autoimmune diseases is described very rarely in the literature so far. There are only few cases of immune-mediated hyperparathyroidism, associated with anti-calcium- sensing receptor autoantibodies, Recent epidemiological studies have shown that coeliac disease is more common than previously thought, with prevalence approaching 1%.Observation : A 47-year-old woman was diagnosed as having coeliac disease ...

Introduction: Prolactin adenomas are the most common pituitary tumors. The aim of treatment is to achieve normal prolactin levels in order to reduce tumor mass and restore the gonadotropic axis. Dopaminergic agonists, including cabergoline, are the standard treatment. But some adenomas can be resistant to this treatment and behave like aggressive tumors. We report the case of a macroprolactinoma resistant to cabergoline.Observation: 50-year-old female pa...